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一名婴儿身上的红斑和紧张性大疱

Erythematous Plaques and Tense Bullae in an Infant.

作者信息

Ederle Amanda, Whisonant Cees T, Nymeyer Hugh

机构信息

Internal Medicine, Baptist Health, Little Rock, USA.

Division of Plastic, Reconstructive, Hand and Burn Surgery, Department of Surgery, University of New Mexico Hospital, Albuquerque, USA.

出版信息

Cureus. 2021 Jul 25;13(7):e16623. doi: 10.7759/cureus.16623. eCollection 2021 Jul.

DOI:10.7759/cureus.16623
PMID:34336533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8319252/
Abstract

Although often thought of as a disease of the elderly, bullous pemphigoid is the second most common bullous disease in infants. Infantile bullous pemphigoid is extremely rare and may be easily confused with other skin diseases such as epidermolysis bullosa and chronic bullous disease of childhood. There appears to be a paucity of literature on unique clinical presentations of infantile bullous pemphigoid. In this report, we describe a case of infantile bullous pemphigoid, which presented with tense bullae in a widespread distribution, including many labial bullae. The rash initially began on this patient's temples and ears four days prior. We believe this case will be of interest as it demonstrates a rare infantile disease with an unusual clinical presentation. It is important to consider infantile bullous pemphigoid in a patient presenting with tense bullae and initiate appropriate diagnostic studies.

摘要

大疱性类天疱疮虽常被认为是一种老年疾病,但却是婴儿中第二常见的大疱性疾病。婴儿型大疱性类天疱疮极为罕见,可能容易与其他皮肤病混淆,如大疱性表皮松解症和儿童慢性大疱性疾病。关于婴儿型大疱性类天疱疮独特临床表现的文献似乎很少。在本报告中,我们描述了一例婴儿型大疱性类天疱疮病例,该病例表现为广泛分布的紧张性水疱,包括许多唇部水疱。皮疹最初于四天前出现在该患者的太阳穴和耳部。我们认为该病例将引起关注,因为它展示了一种具有不寻常临床表现的罕见婴儿疾病。对于出现紧张性水疱的患者,考虑婴儿型大疱性类天疱疮并启动适当的诊断研究很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed81/8319252/463a852596c2/cureus-0013-00000016623-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed81/8319252/2abbfd26d9b3/cureus-0013-00000016623-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed81/8319252/463a852596c2/cureus-0013-00000016623-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed81/8319252/2abbfd26d9b3/cureus-0013-00000016623-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed81/8319252/463a852596c2/cureus-0013-00000016623-i02.jpg

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本文引用的文献

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Long-term evolving profile of childhood autoimmune blistering diseases: Retrospective study on 38 children.儿童自身免疫性疱病的长期演变特征:38 例患儿的回顾性研究。
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Bullous pemphigoid in infants: characteristics, diagnosis and treatment.婴儿大疱性类天疱疮:特征、诊断与治疗
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Increased risk of bullous pemphigoid in male and very old patients: A population-based study on incidence.男性及高龄患者大疱性类天疱疮风险增加:一项基于人群的发病率研究
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