Ahmadi Mohammad Hossein
>Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran.
Bioimpacts. 2021;11(3):169-172. doi: 10.34172/bi.2021.12. Epub 2020 Dec 22.
The coronavirus disease 2019 (COVID-19) is an emerged infectious disease characterized by a severe pneumonia leading to death in some cases. Currently, no licensed vaccines, drugs, or biologics have been confirmed to be absolutely effective in prophylaxis or treatment of this novel infection. Therefore, the treatment of this highly contagious disease remains a global concern and emergency. The viral interference is a competition phenomenon by which a primary virus infecting a cell prohibits the infection of the same cell by another (secondary) virus. The phenomenon has recently been indicated to be exploited for antiviral strategies. This strategy, particularly when there is no efficient drug against a viral infection, is of high importance. Some researchers have studied the application of the phenomenon among different viruses. In this paper, I discussed the possibility of the application of interference phenomenon in prophylaxis of the disease.
2019冠状病毒病（COVID-19）是一种新出现的传染病，其特征是严重肺炎，在某些情况下可导致死亡。目前，尚无经许可的疫苗、药物或生物制品被证实对这种新型感染的预防或治疗绝对有效。因此，这种高传染性疾病的治疗仍然是一个全球关注的问题和紧急情况。病毒干扰是一种竞争现象，即感染细胞的原发性病毒会阻止另一种（继发性）病毒感染同一细胞。最近有迹象表明，这种现象可用于抗病毒策略。这种策略，特别是在没有有效抗病毒药物的情况下，具有重要意义。一些研究人员研究了这种现象在不同病毒中的应用。在本文中，我讨论了干扰现象在该疾病预防中的应用可能性。
