犬蚤过敏性皮炎的免疫发病机制方面
Aspects of the immunopathogenesis of flea allergy dermatitis in dogs.
作者信息
Halliwell R E, Preston J F, Nesbitt J G
机构信息
Department of Medical Sciences, College of Veterinary Medicine, University of Florida, Gainesville.
出版信息
Vet Immunol Immunopathol. 1987 Dec;17(1-4):483-94. doi: 10.1016/0165-2427(87)90164-4.
This paper reviews the current data on the nature of the allergen(s) of the cat flea, Ctenocephalides felis and on some of the factors that determine the development and maintenance of the allergic state. The role of immediate hypersensitivity mediated by IgE, delayed hypersensitivity and of cutaneous basophil hypersensitivity in the immunopathogenesis is discussed. Finally, data on the nature of immunologic non-reactivity is presented and the prospects for therapeutic immunologic intervention discussed.
本文综述了关于猫栉首蚤过敏原性质的现有数据，以及一些决定过敏状态发展和维持的因素。讨论了由IgE介导的速发型超敏反应、迟发型超敏反应和皮肤嗜碱性粒细胞超敏反应在免疫发病机制中的作用。最后，介绍了免疫无反应性的性质数据，并讨论了治疗性免疫干预的前景。
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