Ungerer Garrett, Anwar Taha, Golzy Mojgan, Murray Katie S
University of Missouri School of Medicine, Columbia, MO, USA.
Department of Surgery-Urology Division, University of Missouri, Columbia, MO, USA.
Eur Urol Open Sci. 2020 Jul 31;20:14-19. doi: 10.1016/j.euros.2020.06.007. eCollection 2020 Jul.
Bladder cancer affects life quality, overall health, and mortality negatively. The effect of bladder cancer on activities of daily living (ADLs) is not well established.
To examine the effect of bladder cancer diagnosis on ADLs, in addition to physical, mental, and overall health measures.
Using data from the Surveillance, Epidemiology, and End Results (SEER)-Medicare Health Outcomes Survey (MHOS) registry, responses regarding ADLs and overall health were evaluated in bladder cancer patients over time. The Short Form 12 health survey responses were analyzed to determine the change in physical and mental health scores following bladder cancer diagnosis.
Changes in self-reported ability to perform ADLs and health outcomes following bladder cancer diagnosis were evaluated. Chi-square statistics were used to determine whether the baseline and follow-up surveys were statistically independent for each ADL. Composites scores for physical health (PCS12) and mental health (MCS12) were compared with two-sample test.
A total of 498 patients with surveys before and after bladder cancer diagnosis were identified. An increased percentage of patients reported difficulty in all ADL tasks following bladder cancer diagnosis; this increase was statistically significant for bathing ( = 0.02) and using the toilet ( = 0.03). These patients also reported a significant decline in overall health status ( = 0.0002). A significant reduction in the mean PCS12 and mean MCS12 composite scores was observed ( < 0.0001 and = 0.0003, respectively).
Patients with bladder cancer report a significant decline in functional status and overall health, including both physical and mental well-being after diagnosis. Further study is needed for factors that may be most predictive of the decline in functional independence for this population.
There is a decreased ability to perform daily activities following bladder cancer diagnosis, and patients report a decrease in their physical and mental health. This information can help patients and their caregivers anticipate patient needs following bladder cancer diagnosis, in addition to helping manage their expectations when making decisions regarding treatment options.
膀胱癌对生活质量、整体健康和死亡率有负面影响。膀胱癌对日常生活活动（ADL）的影响尚未明确。
除了身体、心理和整体健康指标外，研究膀胱癌诊断对ADL的影响。
设计、背景和参与者：利用监测、流行病学和最终结果（SEER）-医疗保险健康结果调查（MHOS）登记处的数据，对膀胱癌患者随时间推移关于ADL和整体健康的回答进行评估。分析简短健康调查问卷12（Short Form 12）的回答，以确定膀胱癌诊断后身体和心理健康得分的变化。
评估膀胱癌诊断后自我报告的ADL执行能力和健康结果的变化。卡方统计用于确定每次ADL的基线调查和随访调查在统计学上是否独立。使用双样本检验比较身体健康综合得分（PCS12）和心理健康综合得分（MCS12）。
共确定了498例在膀胱癌诊断前后接受调查的患者。膀胱癌诊断后，报告在所有ADL任务中存在困难的患者比例增加；这种增加在洗澡（P = 0.02）和使用厕所（P = 0.03）方面具有统计学意义。这些患者还报告整体健康状况显著下降（P = 0.0002）。观察到PCS12和MCS12综合得分的平均值显著降低（分别为P < 0.0001和P = 0.0003）。
膀胱癌患者报告功能状态和整体健康显著下降，包括诊断后的身心健康。对于可能最能预测该人群功能独立性下降的因素，需要进一步研究。
膀胱癌诊断后进行日常活动的能力下降，患者报告其身心健康下降。这些信息除了有助于患者及其护理人员在做出治疗选择决策时管理期望外，还能帮助他们预测膀胱癌诊断后的患者需求。
