伽马辐射对黄曲霉毒素的影响。

Effects of gamma irradiation on aflatoxins.

作者信息

Mutluer B, Erkoç F U

机构信息

Turkish Atomic Energy Authority, Lalahan Nuclear Research Institute of Animal Health, Ankara.

出版信息

Z Lebensm Unters Forsch. 1987 Nov;185(5):398-401. doi: 10.1007/BF01042262.

DOI:10.1007/BF01042262

PMID:3433955

Abstract

The effects of gamma irradiation on a mixture of aflatoxins B1, B2, G1, G2 were studied. Standard solutions of A and B were irradiated at 5, 10, and 20 kGy in a solution of water/DMSO (9 + 1, v/v) by using a 137Cs source. The control (0 kGy) and irradiated samples were subjected to RP-HPLC analyses with methanol/water (4 + 5, v/v) as the mobile phase. Aflatoxin B1 (AFB1) was the most radio-sensitive of the four compounds. The radiosensitivity of the other aflatoxins, was in increasing order: G2, B2, G1. Only about 5% of AFB1 remained after irradiation of solution A at 5 kGy. When the concentration of solution B was increased two-fold, trace amounts of AFB1 remained after irradiation doses of 10 and 20 kGy. Irradiation was found to be suitable for the destruction of aflatoxins in solution.

摘要

研究了γ辐照对黄曲霉毒素B1、B2、G1、G2混合物的影响。使用137Cs源，将A和B的标准溶液在水/二甲基亚砜（9 + 1，v/v）溶液中以5、10和20 kGy进行辐照。对照（0 kGy）和辐照后的样品以甲醇/水（4 + 5，v/v）作为流动相进行反相高效液相色谱分析。黄曲霉毒素B1（AFB1）是这四种化合物中对辐射最敏感的。其他黄曲霉毒素的辐射敏感性按升序排列为：G2、B2、G1。溶液A在5 kGy辐照后，仅约5%的AFB1残留。当溶液B的浓度增加两倍时，在10和20 kGy的辐照剂量后仍有痕量的AFB1残留。研究发现辐照适用于破坏溶液中的黄曲霉毒素。