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黄曲霉毒素B1对电离辐射的敏感性。

Sensitivity of aflatoxin b1 to ionizing radiation.

作者信息

Van Dyck P J, Tobback P, Feyes M, van de Voorde H

出版信息

Appl Environ Microbiol. 1982 Jun;43(6):1317-9. doi: 10.1128/aem.43.6.1317-1319.1982.

DOI:10.1128/aem.43.6.1317-1319.1982
PMID:6808920
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC244234/
Abstract

Aflatoxin B1 in a 5-micrograms/ml water solution was sensitive to ionizing radiation. Inactivation was assayed by the Ames microsome mutagenicity test and confirmed by thin-layer chromatography. Destruction of aflatoxin B1 had already begun at 2.5 kilograms (kGy; 1 kGy = 0.1 Mrad), but a dose exceeding 10 kGy was necessary for total destruction.

摘要

5微克/毫升水溶液中的黄曲霉毒素B1对电离辐射敏感。通过艾姆斯微粒体诱变性试验测定其失活情况，并通过薄层色谱法进行确认。黄曲霉毒素B1在2.5千戈瑞（1千戈瑞 = 0.1兆拉德）时就已开始被破坏，但完全破坏需要超过10千戈瑞的剂量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd40/244234/7f5da8d474c4/aem00187-0100-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd40/244234/7f5da8d474c4/aem00187-0100-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd40/244234/7f5da8d474c4/aem00187-0100-a.jpg

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本文引用的文献

1
Aflatoxin contamination of Australian animal feeds and suspected cases of mycotoxicosis.澳大利亚动物饲料中的黄曲霉毒素污染及疑似霉菌毒素中毒病例。
Aust Vet J. 1980 Apr;56(4):176-80. doi: 10.1111/j.1751-0813.1980.tb05674.x.
2
Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test.用沙门氏菌/哺乳动物微粒体诱变性试验检测致癌物和诱变剂的方法。
Mutat Res. 1975 Dec;31(6):347-64. doi: 10.1016/0165-1161(75)90046-1.
γ 射线辐照对食品和饲料作物中黄曲霉毒素 B1 灭活的影响。
Braz J Microbiol. 2008 Oct;39(4):787-91. doi: 10.1590/S1517-838220080004000035. Epub 2008 Dec 1.
4
Inactivation of aflatoxin B1 by using the synergistic effect of hydrogen peroxide and gamma radiation.利用过氧化氢和γ辐射的协同效应使黄曲霉毒素B1失活。
Appl Environ Microbiol. 1989 Feb;55(2):465-7. doi: 10.1128/aem.55.2.465-467.1989.