Peter P, Bron B, Krejs G J, Pelloni S, Brändli H, Blum A L
Z Gastroenterol. 1978 Feb;16(2):66-72.
In four controlled studies on 771 consecutive patients we tested the value of premedication before passing a fiberendoscope. Following local anaesthesia of the throat, 10 mgs of diazepam in patients less than 60 years and 5 mgs in those over 60 years quickly injected intravenously caused a sufficient premedication for fiberendoscopy. Premedication with diazepam is better than placebo. We fell that omission of premedication is not justifiable. Flunitrazepam, for premedication, in doses of 1-2 mgs did not prove to be suitable. 20 patients were radiologically controlled for signs of aspiration following premedication and endoskopy. They showed no signs of aspiration.
在对771例连续患者进行的四项对照研究中，我们测试了在插入纤维内窥镜前进行术前用药的价值。在咽喉局部麻醉后，小于60岁的患者静脉快速注射10毫克地西泮，60岁以上的患者注射5毫克，可为纤维内窥镜检查提供充分的术前用药。用地西泮进行术前用药优于使用安慰剂。我们认为省略术前用药是不合理的。用于术前用药的氟硝西泮，剂量为1 - 2毫克，未被证明是合适的。对20例患者在术前用药和内窥镜检查后进行了放射学检查，以确定有无误吸迹象。他们没有显示出误吸迹象。
