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地西泮和氟硝西泮对氯胺酮麻醉术后不良副作用的影响(作者译)

[Effects of diazepam and flunitrazepam on the undesired postoperative side-effects of ketamine anaesthesia (author's transl)].

作者信息

Knoche E, Traub E, Dick W

出版信息

Anaesthesist. 1978 Jun;27(6):302-8.

PMID:27993
Abstract

150 patients undergoing minor gynaecological procedures (curretages) were anesthetized with ketamine and either diazepam flunitrazepam or placebo in order to establish the best combination for the prevention of postoperative psychotomimetic effects. From observations, up to 24 h after operation, it was found and statistically proven that the combination of ketamine/flunitrazepam as compared to the combinations ketamine/diazepam and ketamine/placebo led to a remarkable reduction of psychotomimetic side reactions.

摘要

150名接受小型妇科手术(刮宫术)的患者用氯胺酮加地西泮、氟硝西泮或安慰剂进行麻醉,以确定预防术后拟精神病效应的最佳组合。通过观察发现,在术后长达24小时内,经统计学证明,与氯胺酮/地西泮和氯胺酮/安慰剂组合相比,氯胺酮/氟硝西泮组合可显著减少拟精神病副作用。

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