Yang Kun, Li Tingying, Zhu Xiaomei, Zou Yun, Liu Dongxian
Department of Dermatology and Venereology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan, 430030, China.
BMC Infect Dis. 2021 Aug 3;21(1):747. doi: 10.1186/s12879-021-06454-4.
Erythema induratum of Bazin (EIB) is a rare cutaneous manifestation of tuberculosis (TB) that frequently occurs in middle-aged women. The clinical manifestations of EIB can mimic various skin diseases, easily leading to misdiagnosis or underdiagnosis. We report a case of a 16-year-old Chinese girl who initially presented with EIB and was subsequently diagnosed with cavitary TB.
The patient is a 16-year-old Chinese girl who presented with clusters of erythematous subcutaneous nodules on the posterior part of her right lower leg matching the clinical manifestations of EIB but was otherwise asymptomatic. The patient was subsequently diagnosed with cavitary TB on the basis of a positive result from a T-SPOT.TB test and the observation of cavitary lung lesions in chest computed tomography scanning. A good clinical response was observed in the patient after the initial phase of a standard 6-month antibiotic regimen.
Adolescents infected with Mycobacterium tuberculosis frequently present atypical symptoms. Cutaneous manifestations of tuberculosis in adolescents can be considered good clinical indicators to predict the underlying disease. Strong clinical suspicion is required for a prompt diagnosis in adolescents with EIB.
巴赞硬红斑（EIB）是一种罕见的结核病（TB）皮肤表现，常见于中年女性。EIB的临床表现可模仿多种皮肤疾病，容易导致误诊或漏诊。我们报告一例16岁中国女孩，最初表现为EIB，随后被诊断为空洞型肺结核。
该患者为一名16岁中国女孩，右小腿后部出现成簇的皮下红斑结节，符合EIB的临床表现，但无其他症状。基于T-SPOT.TB检测结果阳性以及胸部计算机断层扫描中观察到的肺部空洞病变，该患者随后被诊断为空洞型肺结核。在标准的6个月抗生素治疗方案的初始阶段后，观察到患者有良好的临床反应。
感染结核分枝杆菌的青少年常表现出非典型症状。青少年结核病的皮肤表现可被视为预测潜在疾病的良好临床指标。对于患有EIB的青少年，需要高度的临床怀疑才能做出及时诊断。
