Faculty of Medicine, Department of Medical Biochemistry, Kafkas University, Kars, 36100, Turkey.
J Gastrointest Cancer. 2021 Sep;52(3):1081-1085. doi: 10.1007/s12029-021-00680-4. Epub 2021 Aug 4.
Biosensors have become a very interesting field in recent years, thanks to their potential to be converted into self-diagnostic technologies. Being able to analyze a biomarker with different biosensor systems has great potential. This potential is important in terms of time, cost, and practicality with its use in the analysis of difficult-to-diagnose diseases in clinical studies. In this review, the biosensors used in the determination of hepatocellular carcinoma (HCC) biomarkers were compiled. Electrochemical, optical, and piezoelectric biosensors used in the analysis of proteins, DNA, RNA, and cells with varying concentrations in HCC can be designed based on antibodies, nanocomposites, DNA, and aptamers.
近年来，生物传感器在将其转化为自诊断技术方面具有很大的潜力，因此成为一个非常有趣的领域。能够使用不同的生物传感器系统分析生物标志物具有很大的潜力。这种潜力在时间、成本和实用性方面都很重要，因为它可用于临床研究中对难以诊断的疾病进行分析。在这篇综述中，编译了用于测定肝细胞癌 (HCC) 生物标志物的生物传感器。可以基于抗体、纳米复合材料、DNA 和适体，设计用于分析 HCC 中不同浓度的蛋白质、DNA、RNA 和细胞的电化学、光学和压电生物传感器。
