Department of Mathematics, SUNY New Paltz, New Paltz, NY, United States of America.
Department of Biology, SUNY New Paltz, New Paltz, NY, United States of America.
PLoS One. 2021 Aug 4;16(8):e0255236. doi: 10.1371/journal.pone.0255236. eCollection 2021.
Behavioral epidemiology suggests that there is a tight dynamic coupling between the timeline of an epidemic outbreak, and the social response in the affected population (with a typical course involving physical distancing between individuals, avoidance of large gatherings, wearing masks, etc). We study the bidirectional coupling between the epidemic dynamics of COVID-19 and the population social response in the state of New York, between March 1, 2020 (which marks the first confirmed positive diagnosis in the state), until June 20, 2020. This window captures the first state-wide epidemic wave, which peaked to over 11,000 confirmed cases daily in April (making New York one of the US states most severely affected by this first wave), and subsided by the start of June to a count of consistently under 1,500 confirmed cases per day (suggesting temporary state-wide control of the epidemic). In response to the surge in cases, social distancing measures were gradually introduced over two weeks in March, culminating with the PAUSE directive on March 22nd, which mandated statewide shutdown of all nonessential activity. The mandates were then gradually relaxed in stages throughout summer, based on how epidemic benchmarks were met in various New York regions. In our study, we aim to examine on one hand, whether different counties exhibited different responses to the PAUSE centralized measures depending on their epidemic situation immediately preceding PAUSE. On the other hand, we explore whether these different county-wide responses may have contributed in turn to modulating the counties' epidemic timelines. We used the public domain to extract county-wise epidemic measures (such as cumulative and daily incidence of COVID-19), and social mobility measures for different modalities (driving, walking, public transit) and to different destinations. Our correlation analyses between the epidemic and the mobility time series found significant correlations between the size of the epidemic and the degree of mobility drop after PAUSE, as well as between the mobility comeback patterns and the epidemic recovery timeline. In line with existing literature on the role of the population behavioral response during an epidemic outbreak, our results support the potential importance of the PAUSE measures to the control of the first epidemic wave in New York State.
行为流行病学表明,传染病的时间线与受影响人群的社会反应之间存在紧密的动态耦合(典型的过程包括个体之间的物理隔离、避免大型聚会、戴口罩等)。我们研究了 2020 年 3 月 1 日(标志着该州首例确诊阳性病例)至 2020 年 6 月 20 日期间,纽约州的 COVID-19 疫情动态与人群社会反应之间的双向耦合。这一时间段涵盖了第一波全州范围的疫情高峰,4 月每日确诊病例超过 11000 例(使纽约州成为受该波疫情影响最严重的美国州之一),到 6 月初,每日确诊病例数下降到 1500 例以下(表明全州范围内疫情得到暂时控制)。为应对病例激增,3 月两周内逐步引入社会疏远措施,最终于 3 月 22 日发布了 PAUSE 指令,要求全州范围内停止所有非必要活动。随着疫情基准在纽约州各地逐步得到满足,这些指令在夏季分阶段逐步放宽。在我们的研究中,一方面,我们旨在检查不同县在 PAUSE 集中措施方面是否根据 PAUSE 之前的疫情情况表现出不同的反应。另一方面,我们探讨这些不同的全县范围的反应是否反过来对调节各县的疫情时间线有所贡献。我们利用公共领域提取了县一级的疫情措施(如 COVID-19 的累计和每日发病率)以及不同模式(驾驶、步行、公共交通)和不同目的地的社会流动性措施。我们对疫情和流动性时间序列进行的相关分析发现,疫情规模与 PAUSE 后流动性下降程度之间以及流动性恢复模式与疫情恢复时间之间存在显著相关性。与疫情爆发期间人口行为反应的现有文献一致,我们的研究结果支持 PAUSE 措施对纽约州第一波疫情控制的潜在重要性。