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秘鲁强血线虫病的流行情况:系统评价和荟萃分析。

Prevalence of strongyloidiasis in Peru: systematic review and meta-analysis.

机构信息

Medical Practice El Ballestero, Health Service of Castilla La Mancha, Albacete, Spain.

Clinical Medicine Department, University Miguel Hernández of Elche, Ctra N-332, 03550 Sant Joan d'Alacant, Alicante, Spain.

出版信息

BMC Infect Dis. 2021 Aug 4;21(1):755. doi: 10.1186/s12879-021-06441-9.

DOI:10.1186/s12879-021-06441-9
PMID:34348671
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8336367/
Abstract

BACKGROUND

Strongyloidiasis is a disease of great public health significance, caused by the parasitic nematodes Strongyloides stercoralis, Strongyloides fuelleborni, and Strongyloides fuelleborni subsp. kellyi. This systematic review and meta-analysis aimed to assess the prevalence of Strongyloides stercoralis infection in Peru.

METHODS

The review was based on a literature search in PubMed, SciELO and Google Scholar using the key words or root words "strongyl*" AND "Peru" on 15 July 2020. Eligible studies were published from 1 January 1981 to 15 July 2020 and written in English, Spanish, Italian, or French.

RESULTS

We included 21 papers in the analysis. Studies were heterogeneous in terms of study population and diagnostic methods (e.g. Baermann technique, agar, Dancescu or charcoal cultures, serology, string capsule). Prevalence of S. stercoralis ranged from 0.3 to 45%. The pooled proportion of Strongyloides in the general population was 7.34% (95% CI 4.97 to 10.13%). Half the studies were designed to detect parasites in general. In studies designed to detect S. stercoralis, the most widely used diagnostic method was the Baermann technique.

CONCLUSION

Prevalence of S. stercoralis in Peru was high but varied by geographic area, techniques for stool examination, and participant characteristics.

摘要

背景

旋毛虫病是一种具有重要公共卫生意义的疾病,由寄生线虫 Strongyloides stercoralis、Strongyloides fuelleborni 和 Strongyloides fuelleborni subsp. kellyi 引起。本系统评价和荟萃分析旨在评估秘鲁 Strongyloides stercoralis 感染的流行率。

方法

本综述基于 2020 年 7 月 15 日在 PubMed、SciELO 和 Google Scholar 中使用关键字或词根“strongyl*”和“Peru”进行的文献检索。纳入的研究发表于 1981 年 1 月 1 日至 2020 年 7 月 15 日,语言为英语、西班牙语、意大利语或法语。

结果

我们分析了 21 篇论文。这些研究在研究人群和诊断方法(例如贝曼氏技术、琼脂、丹奇斯或木炭培养、血清学、字符串胶囊)方面存在异质性。S. stercoralis 的流行率范围为 0.3%至 45%。一般人群中 Strongyloides 的总流行率为 7.34%(95%CI 4.97%至 10.13%)。一半的研究旨在检测一般寄生虫。在旨在检测 S. stercoralis 的研究中,最广泛使用的诊断方法是贝曼氏技术。

结论

秘鲁的 S. stercoralis 流行率较高,但因地理区域、粪便检查技术和参与者特征而异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84de/8336367/fb2cd404420a/12879_2021_6441_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84de/8336367/2b3521d99f9b/12879_2021_6441_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84de/8336367/39f7bce5dab1/12879_2021_6441_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84de/8336367/6dc518f5c18c/12879_2021_6441_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84de/8336367/fb2cd404420a/12879_2021_6441_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84de/8336367/2b3521d99f9b/12879_2021_6441_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84de/8336367/39f7bce5dab1/12879_2021_6441_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84de/8336367/6dc518f5c18c/12879_2021_6441_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84de/8336367/fb2cd404420a/12879_2021_6441_Fig4_HTML.jpg

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本文引用的文献

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Pathogens. 2020 May 4;9(5):348. doi: 10.3390/pathogens9050348.
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Mapping the Prevalence of Infection in Ecuador: A Serosurvey.厄瓜多尔感染流行情况的绘图:血清学调查。
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