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肥胖和高血压在糖尿病患者中心律失常、缺血性心脏病和心力衰竭的发病中的作用。

Role of obesity and hypertension in the incidence of atrial fibrillation, ischaemic heart disease and heart failure in patients with diabetes.

机构信息

Lab. of Cardiovascular and Dysmetabolic Disease, IRCCS MultiMedica, Milan, Italy.

Dipartimento di Scienze della Salute, Università degli Studi di Milano, Milan, Italy.

出版信息

Cardiovasc Diabetol. 2021 Aug 4;20(1):162. doi: 10.1186/s12933-021-01331-5.

Abstract

In a cohort study performed using primary care databases in a General Practitioners Network, Groenewegen et al. report a clear association between diabetes and incidence of the major chronic progressive heart diseases, notably heart failure (Groenewegen et al. in Cardiovasc Diabetol 20:123, 2021). However, no mention is made of body mass index and hypertension in the methods or in the results. Obesity is linked to hypertension and hypertension is a major risk factor for all cardiovascular diseases, and prospective studies have shown that obesity and hypertension contribute significantly to atrial fibrillation in persons with diabetes. The data would be improved by assessing the role of obesity and of hypertension in the incidence of heart diseases in these patients. This would also lead to a better and personalized treatment of patients with diabetes, for instance through weight loss and intensification of treatment of hypertension, to modify the incidence of atrial fibrillation, ischaemic heart disease and heart failure.

摘要

在全科医生网络的初级保健数据库中进行的一项队列研究中,Groenewegen 等人报告了糖尿病与主要慢性进行性心脏病(特别是心力衰竭)发病率之间的明确关联(Groenewegen 等人,Cardiovasc Diabetol 20:123,2021)。然而,在方法或结果中都没有提到体重指数和高血压。肥胖与高血压有关,高血压是所有心血管疾病的主要危险因素,前瞻性研究表明,肥胖和高血压会显著导致糖尿病患者发生心房颤动。通过评估肥胖和高血压在这些患者心脏病发病率中的作用,数据将得到改善。这也将导致对糖尿病患者进行更好和个性化的治疗,例如通过减肥和加强高血压治疗,以改变心房颤动、缺血性心脏病和心力衰竭的发病率。

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