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口腔鳞状细胞癌患者随访期间生活质量与创伤后成长的综合评估

Combined quality of life and posttraumatic growth evaluation during follow-up care of patients suffering from oral squamous cell carcinoma.

作者信息

Hoene Georg, Gruber Rudolf M, Leonhard Johanna J, Wiechens Bernhard, Schminke Boris, Kauffmann Philipp, Schliephake Henning, Brockmeyer Phillipp

机构信息

Department of Oral and Maxillofacial Surgery, University Medical Center Goettingen, Goettingen D-37575, Germany.

Department of Orthodontics, University Medical Center Goettingen, Goettingen D-37575, Germany.

出版信息

Mol Clin Oncol. 2021 Sep;15(3):189. doi: 10.3892/mco.2021.2351. Epub 2021 Jul 15.

Abstract

Oral cancer therapy is associated with a loss in health-related quality of life (HRQOL) and can also lead to post-traumatic growth (PTG). The current study analyzed the relationship between HRQOL, PTG and influencing clinical factors after treatment. The coherent clinical data of 15 patients were retrospectively analyzed over a 1-year study period. HRQOL and PTG were studied using the University of Washington Quality of Life Version 4 (UW-QOL v4) and Posttraumatic Growth Inventory (PTGI) questionnaires. The results revealed that HRQOL was significantly decreased in a pre- to postoperative manner (P=0.011). Sex demonstrated a nearly significant effect on HRQOL (P=0.058). PTG was experienced the most after surgery, and continuously decreased over the 1-year study period. Patient age had a significant effect on PTG (P=0.040). A significant correlation was also established between HRQOL and PTG (P<0.05). HRQOL and PTG are important influencing factors during postoperative tumor follow-up care and should be simultaneously recorded to address individual patient needs and improve quality of treatment.

摘要

口腔癌治疗会导致健康相关生活质量(HRQOL)下降,也可能引发创伤后成长(PTG)。本研究分析了治疗后HRQOL、PTG与相关临床影响因素之间的关系。在为期1年的研究期间,对15例患者的连贯临床数据进行了回顾性分析。使用华盛顿大学生活质量量表第4版(UW-QOL v4)和创伤后成长量表(PTGI)问卷对HRQOL和PTG进行研究。结果显示,HRQOL在术前至术后显著下降(P = 0.011)。性别对HRQOL有近乎显著的影响(P = 0.058)。PTG在术后最为明显,并在1年的研究期间持续下降。患者年龄对PTG有显著影响(P = 0.040)。HRQOL与PTG之间也建立了显著相关性(P < 0.05)。HRQOL和PTG是术后肿瘤随访期间的重要影响因素,应同时记录以满足个体患者需求并提高治疗质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d416/8327079/521fd715d108/mco-15-03-02351-g00.jpg

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