Watterson J G
Department of Biochemistry, Monash University, Clayton, Vic., Australia.
Biochem J. 1987 Dec 1;248(2):615-7. doi: 10.1042/bj2480615.
The question of a role for water in biochemical and cellular events is ignored by most workers (apart from its obvious role in hydrolysis reactions, which is not under discussion here). But much recent research has pointed to the importance of physical, as well as biochemical, processes of the cell, which focus attention on such straightforward elementary questions as position and relationship in space of cell components. In this communication these questions are examined in terms of a new model of water structure. A radically new feature of this model is that water clusters have long-term rather than flickering existence and are as large as the macromolecular components of the cell. These properties allow the clusters and other components to pack together spatially so giving rise to integrated, large-scale, subcellular structures.
大多数研究人员忽略了水在生化和细胞活动中所起作用的问题（水解反应中其明显作用除外，此处不讨论该作用）。但是最近的许多研究指出了细胞物理过程以及生化过程的重要性，这使得人们关注诸如细胞成分在空间中的位置和关系等简单基本问题。在本通讯中，将根据一种新的水结构模型来研究这些问题。该模型的一个全新特征是水簇具有长期存在而非瞬间即逝的特性，并且其大小与细胞的大分子成分相当。这些特性使得水簇和其他成分能够在空间上聚集在一起，从而形成整合的、大规模的亚细胞结构。
