Clegg J S
J Cell Biol. 1984 Jul;99(1 Pt 2):167s-171s. doi: 10.1083/jcb.99.1.167s.
The extent to which the properties of water in cells are like those of water in dilute aqueous solutions is a question of broad significance to cell biology. A detailed answer is not available at present, although evidence is accumulating that the properties of at least a large fraction of intracellular water are altered by interactions with cell ultrastructure, notably the cytomatrix. That and related evidence also suggests that the properties, composition, and activities of the "aqueous cytoplasm" of intact cells bear little resemblance to those of the "cytosol" obtained by cell fractionation. This paper will consider some of the evidence for these possibilities and some of their potential consequences with regard to cellular structure and function.
细胞内水的性质与稀水溶液中水的性质相似的程度，是细胞生物学中一个具有广泛意义的问题。目前尚无详细答案，尽管越来越多的证据表明，至少大部分细胞内水的性质会因与细胞超微结构（尤其是细胞基质）的相互作用而改变。这一证据以及相关证据还表明，完整细胞的“水性细胞质”的性质、组成和活性与通过细胞分级分离获得的“胞质溶胶”几乎没有相似之处。本文将探讨这些可能性的一些证据，以及它们对细胞结构和功能的一些潜在影响。
