2021 年 2 月至 5 月，荷兰针对确诊病例的家庭和其他密切接触者的 SARS-CoV-2 传播和感染的疫苗有效性。
Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021.
机构信息
Center for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
GGD Brabant Zuidoost, Eindhoven, the Netherlands.
出版信息
Euro Surveill. 2021 Aug;26(31). doi: 10.2807/1560-7917.ES.2021.26.31.2100640.
Several studies report high effectiveness of COVID-19 vaccines against SARS-CoV-2 infection and severe disease, however an important knowledge gap is the vaccine effectiveness against transmission (VET). We present estimates of the VET to household and other close contacts in the Netherlands, from February to May 2021, using contact monitoring data. The secondary attack rate among household contacts was lower for fully vaccinated than unvaccinated index cases (11% vs 31%), with an adjusted VET of 71% (95% confidence interval: 63-77).
多项研究报告表明，COVID-19 疫苗对 SARS-CoV-2 感染和重症疾病具有高度有效性，然而，疫苗对传播的有效性（VET）仍是一个重要的知识空白。我们利用接触监测数据，报告了 2021 年 2 月至 5 月期间荷兰家庭和其他密切接触者的 VET 估计值。与未接种疫苗的对照病例相比，完全接种疫苗的家庭接触者的二次感染率较低（11%对 31%），调整后的 VET 为 71%（95%置信区间：63-77）。
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