da Rosa Samir Ezequiel, Costa Amina Chain, Fortes Marcos S R, Marson Runer Augusto, Neves Eduardo Borba, Rodrigues Laercio Camilo, Ferreira Paula Fernandez, Filho Jose Fernandes
Brazilian Army Physical Fitness Research Institute (IPCFEx), Rio de Janeiro 22291-090, Brazil.
Federal Fluminense University (UFF), Niterói 24210-240, Brazil.
Healthcare (Basel). 2021 Jul 14;9(7):886. doi: 10.3390/healthcare9070886.
Visceral adipose tissue (VAT) has high metabolic activity and secretes a larger number of adipokines that are related to the inflammatory process. Quantifying VAT could estimate the risk of developing Metabolic Syndrome (MetS). This study was designed to determine the VAT cut-off points assessed by DXA associated with MetS in military men. In total, 270 (37.5 ± 6.9 years) military men from the Brazilian Army (BA) participated in the study. Anthropometric measurements, assessment of body composition by dual X-ray absorptiometry (DXA), hemodynamics and biochemical tests were performed. The Student's test, independent samples, Person's correlation, ROC curve, Youden Index and positive (PPV) and negative predictive value (NPV) were used. The MetS prevalence was 27.4%, which means that 74 (38.0 ± 7.3 years) military men had at least three risk factors of MetS present. The cutoff point of VAT with the highest balance between sensitivity (77.0%) and specificity (69.9%) was 1025.0 cm (1086.0 g). An area on the ROC curve was 0.801 ( < 0.000), which was very good precision. VAT ≥ 1025.0 cm (1086.0 g) is associated with the risk factors of MetS and is, therefore, a predictor of the disease with good indicators of sensitivity and specificity and a robust indicator of MetS.
内脏脂肪组织（VAT）具有高代谢活性，可分泌大量与炎症过程相关的脂肪因子。量化内脏脂肪组织能够评估发生代谢综合征（MetS）的风险。本研究旨在确定通过双能X线吸收法（DXA）评估的、与军人代谢综合征相关的内脏脂肪组织截断点。共有270名（37.5±6.9岁）来自巴西陆军（BA）的军人参与了本研究。进行了人体测量、通过双能X线吸收法（DXA）评估身体成分、血流动力学和生化检测。使用了独立样本t检验、Person相关性分析、ROC曲线、约登指数以及阳性预测值（PPV）和阴性预测值（NPV）。代谢综合征的患病率为27.4%，这意味着74名（38.0±7.3岁）军人至少存在三种代谢综合征风险因素。在敏感性（77.0%）和特异性（69.9%）之间具有最高平衡的内脏脂肪组织截断点为1025.0 cm³（1086.0 g）。ROC曲线下面积为0.801（P<0.000），精度非常好。内脏脂肪组织≥1025.0 cm³（1086.0 g）与代谢综合征的风险因素相关，因此是该疾病的一个预测指标，具有良好的敏感性和特异性指标，是代谢综合征的一个可靠指标。
