Suppr超能文献

骨少肌少症——双能X线吸收法(DXA)在诊断中的作用

Osteosarcopenia-The Role of Dual-Energy X-ray Absorptiometry (DXA) in Diagnostics.

作者信息

Gonera-Furman Aleksandra, Bolanowski Marek, Jędrzejuk Diana

机构信息

Department of Endocrinology, Diabetes and Isotope Therapy, Jan Mikulicz-Radecki University Clinical Hospital, 50-556 Wroclaw, Poland.

Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University, 50-367 Wroclaw, Poland.

出版信息

J Clin Med. 2022 Apr 30;11(9):2522. doi: 10.3390/jcm11092522.

Abstract

Osteoporosis and sarcopenia lead to increased mortality, but their early diagnosis allows preventive measures and treatment to be implemented. The dual-energy X-ray absorptiometry (DXA) method enables the assessment of both bone mineral density (BMD) and bone quality based on the trabecular bone score (TBS), the Bone Strain Index (BSI), hip structure analysis (HSA), and comprehensive hip axis length (HAL). The main complications of osteoporosis are fractures, and a BMD value or T-score together with TBS can be also applied in fracture risk calculation using the Fracture Risk Assessment Tool (FRAX). In recent years, the interest in sarcopenia has increased. There are many methods for assessing the quality, quantity and function of muscles. Total body DXA provides information not only about the BMD of the whole skeleton or the amount of lean tissue (identified as fat-free mass), but also about the amount and distribution of adipose tissue. Some parameters obtained from DXA measurements related to muscle and/or fat mass are used in the assessment of osteosarcopenia. The following article presents a wide range of possibilities for the use of the DXA method in the diagnosis of osteosarcopenia because DXA is a useful technique for the diagnosis of bone density and body composition together.

摘要

骨质疏松症和肌肉减少症会导致死亡率上升,但它们的早期诊断可使预防措施和治疗得以实施。双能X线吸收法(DXA)能够基于小梁骨评分(TBS)、骨应变指数(BSI)、髋部结构分析(HSA)和综合髋轴长度(HAL)来评估骨矿物质密度(BMD)和骨质。骨质疏松症的主要并发症是骨折,BMD值或T值以及TBS也可用于使用骨折风险评估工具(FRAX)计算骨折风险。近年来,人们对肌肉减少症的关注度有所增加。有许多方法可用于评估肌肉的质量、数量和功能。全身DXA不仅能提供关于整个骨骼的BMD或瘦组织量(定义为去脂体重)的信息,还能提供关于脂肪组织的量和分布的信息。从DXA测量中获得的一些与肌肉和/或脂肪量相关的参数用于评估骨质疏松症合并肌肉减少症。以下文章介绍了DXA方法在骨质疏松症合并肌肉减少症诊断中的广泛应用可能性,因为DXA是一种同时诊断骨密度和身体成分的有用技术。

相似文献

引用本文的文献

本文引用的文献

1
Assessment of Muscle Quantity, Quality and Function.肌肉数量、质量和功能的评估
J Obes Metab Syndr. 2022 Mar 30;31(1):9-16. doi: 10.7570/jomes22025.
5
Myokines in Acromegaly: An Altered Irisin Profile.肢端肥大症中的肌肉因子:鸢尾素谱的改变。
Front Endocrinol (Lausanne). 2021 Nov 2;12:728734. doi: 10.3389/fendo.2021.728734. eCollection 2021.
6
New DXA Diagnostic Indexes of Abdominal Obesity.腹部肥胖的新型双能X线吸收法诊断指标
Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2021 Oct 26;42(2):37-50. doi: 10.2478/prilozi-2021-0020.
10
Fracture risk assessment by the FRAX model.采用FRAX模型进行骨折风险评估。
Climacteric. 2022 Feb;25(1):22-28. doi: 10.1080/13697137.2021.1945027. Epub 2021 Jul 28.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验