改性斜发沸石基吸附剂对降低产蛋鸡赭曲霉毒素 A 有害影响的效果。

Efficacy of a Modified Clinoptilolite Based Adsorbent in Reducing Detrimental Effects of Ochratoxin A in Laying Hens.

机构信息

The Faculty of Veterinary Medicine, University of Belgrade, Bulevar oslobodjenja 18, 11000 Belgrade, Serbia.

Department of Pathology, Faculty of Veterinary Medicine, University of Belgrade, Bulevar oslobodjenja 18, 11000 Belgrade, Serbia.

出版信息

Toxins (Basel). 2021 Jul 7;13(7):469. doi: 10.3390/toxins13070469.

BACKGROUND

The objective of this study was to evaluate the efficacy of modified clinoptilolite (Minazel Plus, MZ) as a mycotoxin adsorbent for preventing the negative the effects of ochratoxin A (OTA) on performance, pathohistological changes, and OTA residue in the eggs of laying hens.

METHODS

Forty eight ( = 48) laying hens (27 weeks old) were equally divided into six groups and depending on the type of addition were allocated to the following experimental treatments for 7 weeks: E-I group-1 mg/kg OTA; E-II group 0.25 mg/kg OTA; E-III group 1 mg/kg OTA + 0.2% of MZ; E-IV group 0.25 mg/kg OTA + 0.2% of MZ; MZ group supplemented with 0.2% of the adsorbent; and control (K, without feed additive).

RESULTS

Overall, the addition of 0.2% MZ to laying hen feed mitigated the harmful effects of OTA on target organs and reduced the presence of OTA residue in eggs. The groups that received 0.2% of MZ achieved better production results in terms of body weight, number of eggs, and feed consumption, compared to the other treatments.

CONCLUSIONS

The current findings confirm the efficacy of MZ in preventing performance losses in laying hens exposed to OTA, as well as for improving the welfare and health of food producing animals.

背景

本研究旨在评估改性沸石（Minazel Plus，MZ）作为霉菌毒素吸附剂预防赭曲霉毒素 A（OTA）对产蛋鸡性能、组织病理学变化和蛋中 OTA 残留的负面影响的功效。

方法

48 只（ = 48）产蛋鸡（27 周龄）平均分为 6 组，根据添加物的类型分为以下 6 个实验处理组，处理 7 周：E-I 组 1 mg/kg OTA；E-II 组 0.25 mg/kg OTA；E-III 组 1 mg/kg OTA+0.2% MZ；E-IV 组 0.25 mg/kg OTA+0.2% MZ；MZ 组添加 0.2%吸附剂；对照组（K，无饲料添加剂）。