The Faculty of Veterinary Medicine, University of Belgrade, Bulevar oslobodjenja 18, 11000 Belgrade, Serbia.
Department of Pathology, Faculty of Veterinary Medicine, University of Belgrade, Bulevar oslobodjenja 18, 11000 Belgrade, Serbia.
Toxins (Basel). 2021 Jul 7;13(7):469. doi: 10.3390/toxins13070469.
The objective of this study was to evaluate the efficacy of modified clinoptilolite (Minazel Plus, MZ) as a mycotoxin adsorbent for preventing the negative the effects of ochratoxin A (OTA) on performance, pathohistological changes, and OTA residue in the eggs of laying hens.
Forty eight ( = 48) laying hens (27 weeks old) were equally divided into six groups and depending on the type of addition were allocated to the following experimental treatments for 7 weeks: E-I group-1 mg/kg OTA; E-II group 0.25 mg/kg OTA; E-III group 1 mg/kg OTA + 0.2% of MZ; E-IV group 0.25 mg/kg OTA + 0.2% of MZ; MZ group supplemented with 0.2% of the adsorbent; and control (K, without feed additive).
Overall, the addition of 0.2% MZ to laying hen feed mitigated the harmful effects of OTA on target organs and reduced the presence of OTA residue in eggs. The groups that received 0.2% of MZ achieved better production results in terms of body weight, number of eggs, and feed consumption, compared to the other treatments.
The current findings confirm the efficacy of MZ in preventing performance losses in laying hens exposed to OTA, as well as for improving the welfare and health of food producing animals.
本研究旨在评估改性沸石（Minazel Plus，MZ）作为霉菌毒素吸附剂预防赭曲霉毒素 A（OTA）对产蛋鸡性能、组织病理学变化和蛋中 OTA 残留的负面影响的功效。
48 只（ = 48）产蛋鸡（27 周龄）平均分为 6 组，根据添加物的类型分为以下 6 个实验处理组，处理 7 周：E-I 组 1 mg/kg OTA；E-II 组 0.25 mg/kg OTA；E-III 组 1 mg/kg OTA+0.2% MZ；E-IV 组 0.25 mg/kg OTA+0.2% MZ；MZ 组添加 0.2%吸附剂；对照组（K，无饲料添加剂）。
总体而言，在产蛋鸡饲料中添加 0.2% MZ 减轻了 OTA 对靶器官的有害影响，并降低了鸡蛋中 OTA 残留量。与其他处理相比，添加 0.2% MZ 的组在体重、蛋数和饲料消耗方面取得了更好的生产效果。
本研究结果证实了 MZ 预防暴露于 OTA 的产蛋鸡性能下降以及改善生产动物福利和健康的功效。
