Department of Dermatology, Huadong Hospital, Fudan University, Shanghai 200040, People's Republic of China.
Department of Pathology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai 200050, People's Republic of China.
Photodiagnosis Photodyn Ther. 2021 Sep;35:102474. doi: 10.1016/j.pdpdt.2021.102474. Epub 2021 Aug 3.
Keratoacanthoma (KA)-like squamous cell carcinoma (SCC) is inclined to be diagnosed as KA due to its resemblance to KA in appearance. A giant facial KA-like SCC has aggressive growth and malignant metastasis, and seriously affects health and aesthetics. Prompt and appropriate treatment is extremely crucial and is a great challenge. Herein, we report a case of surgery combined with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in the successful management of a giant KA-like SCC in the left eyebrow of an elderly woman, providing reference for more efficient disposal of such cases in clinic.
角化棘皮瘤（KA）样鳞状细胞癌（SCC）因其外观与 KA 相似，容易被误诊为 KA。巨大面部 KA 样 SCC 生长侵袭性强，恶性转移，严重影响健康和美观。及时、恰当的治疗极为关键，极具挑战性。本研究报道了一例老年女性左侧眉部巨大 KA 样 SCC 经手术联合 5-氨基酮戊酸光动力疗法（ALA-PDT）成功治疗的病例，为临床处理此类病例提供了更有效的参考。
