Department of Gastroenterology, Royal Wolverhampton NHS Trust, Wolverhampton, United Kingdom.
Gastroenterology Department, Valduce Hospital, Como, Italy.
Endoscopy. 2021 Sep;53(9):947-969. doi: 10.1055/a-1547-2282. Epub 2021 Aug 6.
This is a collaboration between the British Society of Gastroenterology (BSG) and the European Society of Gastrointestinal Endoscopy (ESGE), and is a scheduled update of their 2016 guideline on endoscopy in patients on antiplatelet or anticoagulant therapy. The guideline development committee included representatives from the British Society of Haematology, the British Cardiovascular Intervention Society, and two patient representatives from the charities Anticoagulation UK and Thrombosis UK, as well as gastroenterologists. The process conformed to AGREE II principles, and the quality of evidence and strength of recommendations were derived using GRADE methodology. Prior to submission for publication, consultation was made with all member societies of ESGE, including BSG. Evidence-based revisions have been made to the risk categories for endoscopic procedures, and to the categories for risks of thrombosis. In particular a more detailed risk analysis for atrial fibrillation has been employed, and the recommendations for direct oral anticoagulants have been strengthened in light of trial data published since the previous version. A section has been added on the management of patients presenting with acute GI haemorrhage. Important patient considerations are highlighted. Recommendations are based on the risk balance between thrombosis and haemorrhage in given situations.
这是英国胃肠病学会(BSG)与欧洲胃肠道内镜学会(ESGE)之间的合作,是对其 2016 年关于抗血小板或抗凝治疗患者内镜检查指南的定期更新。指南制定委员会包括来自英国血液学学会、英国心血管介入学会的代表,以及来自慈善机构抗凝英国和血栓英国的两名患者代表,以及胃肠病学家。该过程符合 AGREE II 原则,证据质量和推荐强度使用 GRADE 方法得出。在提交发表之前,已向 ESGE 的所有成员协会进行了咨询,包括 BSG。已经对内镜检查程序的风险类别和血栓形成的风险类别进行了基于证据的修订。特别是,对心房颤动进行了更详细的风险分析,并根据自前一版本以来发表的试验数据,加强了对直接口服抗凝剂的建议。增加了关于急性胃肠道出血患者管理的部分。强调了重要的患者注意事项。建议是基于特定情况下血栓形成和出血之间的风险平衡。