Lee Bao-Hong, Hsu Wei-Hsuan, Chien Hao-Yuan, Hou Chih-Yao, Hsu Ya-Ting, Chen You-Zuo, Wu She-Ching
Department of Horticulture, National Chiayi University, Chiayi 600355, Taiwan.
Department of Food Safety/Hygiene and Risk Management, College of Medicine, National Cheng Kung University, Tainan 701401, Taiwan.
Foods. 2021 Jul 14;10(7):1631. doi: 10.3390/foods10071631.
infection (CDI) is a large intestine disease caused by toxins produced by the spore-forming bacterium , which belongs to Gram-positive bacillus. Using antibiotics treatment disturbances in the gut microbiota and toxins produced by disrupt the intestinal barrier. Some evidence indicates fecal microbiota transplantation and probiotics may decrease the risk of CDI recurrence. This study aimed to evaluate the efficacy of fermented mango by using the lactic acid bacteria and develop innovative products in the form of fermented mango jam. -fermented mango products inhibited the growth of while promoting the growth of next-generation probiotic . Both supernatant and precipitate of mango-fermented products prevented cell death in gut enterocyte-like Caco-2 cells against infection. Mango-fermented products also protected gut barrier function by elevating the expression of tight junction proteins. Moreover, -fermented mango jam with high hydrostatic pressure treatment had favorable textural characteristics and sensory quality.
艰难梭菌感染(CDI)是一种由形成孢子的细菌产生的毒素引起的大肠疾病,该细菌属于革兰氏阳性杆菌。使用抗生素治疗会扰乱肠道微生物群,并且该细菌产生的毒素会破坏肠道屏障。一些证据表明,粪便微生物群移植和益生菌可能会降低CDI复发的风险。本研究旨在评估使用乳酸菌发酵芒果的功效,并开发发酵芒果酱形式的创新产品。[乳酸菌名称]发酵芒果产品抑制了[艰难梭菌名称]的生长,同时促进了下一代益生菌[益生菌名称]的生长。芒果发酵产品的上清液和沉淀物都能防止肠道肠上皮样Caco-2细胞因[艰难梭菌名称]感染而死亡。芒果发酵产品还通过提高紧密连接蛋白的表达来保护肠道屏障功能。此外,经过高静水压处理的[乳酸菌名称]发酵芒果酱具有良好的质地特性和感官品质。