• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Quality control requirements for the correct annotation of lipidomics data.

作者信息

Köfeler Harald C, Eichmann Thomas O, Ahrends Robert, Bowden John A, Danne-Rasche Niklas, Dennis Edward A, Fedorova Maria, Griffiths William J, Han Xianlin, Hartler Jürgen, Holčapek Michal, Jirásko Robert, Koelmel Jeremy P, Ejsing Christer S, Liebisch Gerhard, Ni Zhixu, O'Donnell Valerie B, Quehenberger Oswald, Schwudke Dominik, Shevchenko Andrej, Wakelam Michael J O, Wenk Markus R, Wolrab Denise, Ekroos Kim

机构信息

Core Facility Mass Spectrometry and Lipidomics, ZMF, Medical University of Graz, Graz, Austria.

Institute for Molecular Biosciences, Karl-Franzens University of Graz, Graz, Austria.

出版信息

Nat Commun. 2021 Aug 6;12(1):4771. doi: 10.1038/s41467-021-24984-y.

DOI:10.1038/s41467-021-24984-y
PMID:34362906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8346590/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b556/8346590/f9ffe8f32a3a/41467_2021_24984_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b556/8346590/f9ffe8f32a3a/41467_2021_24984_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b556/8346590/f9ffe8f32a3a/41467_2021_24984_Fig1_HTML.jpg

相似文献

1
Quality control requirements for the correct annotation of lipidomics data.脂质组学数据正确注释的质量控制要求。
Nat Commun. 2021 Aug 6;12(1):4771. doi: 10.1038/s41467-021-24984-y.
2
Reply to "Quality control requirements for the correct annotation of lipidomics data".对《脂质组学数据正确注释的质量控制要求》的回复
Nat Commun. 2021 Aug 6;12(1):4772. doi: 10.1038/s41467-021-24985-x.
3
Metabolomics and Lipidomics Profiling in Asymptomatic Severe Intracranial Arterial Stenosis: Results from a Population-Based Study.无症状性严重颅内动脉狭窄的代谢组学和脂质组学特征:一项基于人群的研究结果。
J Proteome Res. 2020 Jun 5;19(6):2206-2216. doi: 10.1021/acs.jproteome.9b00644. Epub 2020 Apr 23.
4
Metabolomics meets lipidomics: Assessing the small molecule component of metabolism.代谢组学与脂质组学相遇:评估代谢的小分子成分。
Bioessays. 2020 Dec;42(12):e2000052. doi: 10.1002/bies.202000052.
5
Integrated non-targeted lipidomics and metabolomics analyses for fluctuations of neonicotinoids imidacloprid and acetamiprid on Neuro-2a cells.整合非靶向脂质组学和代谢组学分析研究新烟碱类农药吡虫啉和噻虫胺对 Neuro-2a 细胞的影响。
Environ Pollut. 2021 Sep 1;284:117327. doi: 10.1016/j.envpol.2021.117327. Epub 2021 May 7.
6
Metabolomics, Lipidomics, and Immunometabolism.代谢组学、脂质组学和免疫代谢组学。
Methods Mol Biol. 2021;2285:319-328. doi: 10.1007/978-1-0716-1311-5_24.
7
Integration of lipidomics and metabolomics for in-depth understanding of cellular mechanism and disease progression.脂质组学和代谢组学的整合,深入了解细胞机制和疾病进展。
J Genet Genomics. 2020 Feb 20;47(2):69-83. doi: 10.1016/j.jgg.2019.11.009. Epub 2019 Dec 18.
8
NIST lipidomics workflow questionnaire: an assessment of community-wide methodologies and perspectives.NIST 脂质组学工作流程调查问卷:对全社区方法和观点的评估。
Metabolomics. 2018 Mar 20;14(5):53. doi: 10.1007/s11306-018-1340-1.
9
Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry-Based Metabolomics and Lipidomics Identify Biomarkers for Efficacy Evaluation of Mesalazine in a Dextran Sulfate Sodium-Induced Ulcerative Colitis Mouse Model.基于超高效液相色谱-四极杆飞行时间质谱联用的代谢组学和脂质组学鉴定美沙拉嗪在葡聚糖硫酸钠诱导的溃疡性结肠炎小鼠模型中疗效评价的生物标志物。
J Proteome Res. 2021 Feb 5;20(2):1371-1381. doi: 10.1021/acs.jproteome.0c00757. Epub 2020 Dec 23.
10
Metabolomics and lipidomics study unveils the impact of polybrominated diphenyl ether-47 on breast cancer mice.代谢组学和脂质组学研究揭示多溴联苯醚-47 对乳腺癌小鼠的影响。
J Hazard Mater. 2020 May 15;390:121451. doi: 10.1016/j.jhazmat.2019.121451. Epub 2019 Oct 13.

引用本文的文献

1
Circulating Lipid Profiles Indicate Incomplete Metabolic Recovery After Weight Loss, Suggesting the Need for Additional Interventions in Severe Obesity.循环脂质谱表明减肥后代谢未完全恢复,提示重度肥胖患者需要额外的干预措施。
Biomolecules. 2025 Aug 1;15(8):1112. doi: 10.3390/biom15081112.
2
A chimeric Mla-Pqi lipid transport system is required for Brucella abortus survival in macrophages.布鲁氏菌在巨噬细胞中存活需要嵌合的Mla-Pqi脂质转运系统。
EMBO J. 2025 Aug 13. doi: 10.1038/s44318-025-00511-3.
3
Introduction of a Lipidomics Scoring System for data quality assessment.

本文引用的文献

1
Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures.脂质图谱分类、命名和 MS 衍生脂质结构的缩写更新。
J Lipid Res. 2020 Dec;61(12):1539-1555. doi: 10.1194/jlr.S120001025. Epub 2020 Oct 9.
2
Automated Annotation of Sphingolipids Including Accurate Identification of Hydroxylation Sites Using MS Data.基于 MS 数据的神经酰胺类化合物自动注释及羟基化位点的准确鉴定
Anal Chem. 2020 Oct 20;92(20):14054-14062. doi: 10.1021/acs.analchem.0c03016. Epub 2020 Oct 1.
3
Lipidomics needs more standardization.
用于数据质量评估的脂质组学评分系统介绍。
J Lipid Res. 2025 Apr 30:100817. doi: 10.1016/j.jlr.2025.100817.
4
Quality evaluation of metabolite annotation based on comprehensive simulation of MS/MS data from high-resolution mass spectrometry (HRMS) and similarity scoring.基于高分辨率质谱(HRMS)的MS/MS数据综合模拟和相似性评分的代谢物注释质量评估
Anal Bioanal Chem. 2025 Jun;417(14):3061-3077. doi: 10.1007/s00216-025-05847-7. Epub 2025 Apr 18.
5
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective.细胞外囊泡制剂的定量脂质分析:一种观点。
J Extracell Vesicles. 2025 Mar;14(3):e70049. doi: 10.1002/jev2.70049.
6
Introducing "Identification Probability" for Automated and Transferable Assessment of Metabolite Identification Confidence in Metabolomics and Related Studies.介绍用于代谢组学及相关研究中代谢物鉴定置信度的自动化和可转移评估的“鉴定概率”。
Anal Chem. 2025 Jan 14;97(1):1-11. doi: 10.1021/acs.analchem.4c04060. Epub 2024 Dec 19.
7
Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors.多平台代谢组学对来自杂食者和素食者供体的全人粪便候选参比材料的实验室间研究。
Metabolomics. 2024 Nov 4;20(6):125. doi: 10.1007/s11306-024-02185-0.
8
Highly reliable LC-MS lipidomics database for efficient human plasma profiling based on NIST SRM 1950.基于 NIST SRM 1950 的高效人血浆分析用高可靠性 LC-MS 脂质组学数据库。
J Lipid Res. 2024 Nov;65(11):100671. doi: 10.1016/j.jlr.2024.100671. Epub 2024 Oct 10.
9
Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards.通过真实标准,在人类血浆参考物质中获得一致的实验室间衍生神经酰胺浓度。
Nat Commun. 2024 Oct 3;15(1):8562. doi: 10.1038/s41467-024-52087-x.
10
Introducing 'identification probability' for automated and transferable assessment of metabolite identification confidence in metabolomics and related studies.引入“识别概率”用于代谢组学及相关研究中代谢物识别可信度的自动化和可转移评估。
bioRxiv. 2024 Jul 31:2024.07.30.605945. doi: 10.1101/2024.07.30.605945.
脂质组学需要更多的标准化。
Nat Metab. 2019 Aug;1(8):745-747. doi: 10.1038/s42255-019-0094-z.
4
A lipidome atlas in MS-DIAL 4.MS-DIAL 4 中的脂质组图谱
Nat Biotechnol. 2020 Oct;38(10):1159-1163. doi: 10.1038/s41587-020-0531-2. Epub 2020 Jun 15.
5
Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts.被困离子淌度谱和 PASEF 能够从最小量的样本中进行深入的脂质组学分析。
Nat Commun. 2020 Jan 16;11(1):331. doi: 10.1038/s41467-019-14044-x.
6
Nano-LC/NSI MS Refines Lipidomics by Enhancing Lipid Coverage, Measurement Sensitivity, and Linear Dynamic Range.纳米级液相色谱/纳升电喷雾串联质谱通过提高脂质覆盖率、检测灵敏度和线性动态范围来完善脂质组学研究。
Anal Chem. 2018 Jul 3;90(13):8093-8101. doi: 10.1021/acs.analchem.8b01275. Epub 2018 Jun 11.
7
Deciphering lipid structures based on platform-independent decision rules.基于平台无关决策规则解析脂质结构。
Nat Methods. 2017 Dec;14(12):1171-1174. doi: 10.1038/nmeth.4470. Epub 2017 Oct 23.
8
LipidHunter Identifies Phospholipids by High-Throughput Processing of LC-MS and Shotgun Lipidomics Datasets.LipidHunter通过对LC-MS和鸟枪法脂质组学数据集进行高通量处理来鉴定磷脂。
Anal Chem. 2017 Sep 5;89(17):8800-8807. doi: 10.1021/acs.analchem.7b01126. Epub 2017 Aug 8.
9
LipidMatch: an automated workflow for rule-based lipid identification using untargeted high-resolution tandem mass spectrometry data.LipidMatch:一种使用非靶向高分辨率串联质谱数据进行基于规则的脂质鉴定的自动化工作流程。
BMC Bioinformatics. 2017 Jul 10;18(1):331. doi: 10.1186/s12859-017-1744-3.
10
Retention behavior of lipids in reversed-phase ultrahigh-performance liquid chromatography-electrospray ionization mass spectrometry.脂质在反相超高效液相色谱-电喷雾电离质谱中的保留行为
J Chromatogr A. 2016 Jun 10;1450:76-85. doi: 10.1016/j.chroma.2016.04.082. Epub 2016 May 3.