Stenvinkel Peter, Avesani Carla M, Gordon Line J, Schalling Martin, Shiels Paul G
Division of Renal Medicine, Department of Clinical Science, Technology and Intervention, Karolinska Institutet, Stockholm, Sweden.
Stockholm Resilience Centre Stockholm University, Stockholm, Sweden.
J Clin Transl Sci. 2021 May 17;5(1):e128. doi: 10.1017/cts.2021.790. eCollection 2021.
Homo sapiens is currently living in serious disharmony with the rest of the natural world. For our species to survive, and for our well-being, we must gather knowledge from multiple perspectives and actively engage in studies of planetary health. The enormous diversity of species, one of the most striking aspects of life on our planet, provides a source of solutions that have been developed through evolution by natural selection by animals living in extreme environments. The food system is central to finding solutions; our current global eating patterns have a negative impact on human health, driven climate change and loss of biodiversity. We propose that the use of solutions derived from nature, an approach termed biomimetics, could mitigate the effects of a changing climate on planetary health as well as human health. For example, activation of the transcription factor Nrf2 may play a role in protecting animals living in extreme environments, or animals exposed to heat stress, pollution and pesticides. In order to meet these challenges, we call for the creation of novel interdisciplinary planetary health research teams.
智人目前正与自然界的其他部分处于严重的不和谐状态。为了我们这个物种的生存以及我们的福祉，我们必须从多个角度收集知识，并积极参与地球健康研究。物种的巨大多样性是我们星球生命最显著的特征之一，它提供了一系列解决方案，这些方案是生活在极端环境中的动物通过自然选择进化而来的。食物系统是找到解决方案的核心；我们当前的全球饮食模式对人类健康产生了负面影响，推动了气候变化并导致生物多样性丧失。我们建议利用源自自然的解决方案，即一种称为仿生学的方法，可以减轻气候变化对地球健康以及人类健康的影响。例如，转录因子Nrf2的激活可能在保护生活在极端环境中的动物，或暴露于热应激、污染和杀虫剂的动物方面发挥作用。为了应对这些挑战，我们呼吁创建新的跨学科地球健康研究团队。
