Graduate School of Medicine, Health Sciences, Division of Radiological Examination and Technology, Tohoku University, Sendai City, Japan.
Department of Diagnostic imaging & Nuclear Medicine, Tokyo Women's Medical University, Tokyo, Japan.
J Appl Clin Med Phys. 2021 Sep;22(9):307-312. doi: 10.1002/acm2.13390. Epub 2021 Aug 10.
The area detector 320-row CT scanner, which can cover the whole heart in one rotation, can aid in reducing radiation exposure during electrocardiography (ECG)-gated coronary CT angiography (CCTA). Recently, researchers have proposed dose-modulated dynamic CCTA with a 320-row scanner for the detection of functional myocardial ischemia. In the present study, we compared and validated the radiation dose of this method with that of the standard CCTA method and the latest diagnostic reference levels (DRLs).
The study included a total of 164 consecutive patients with suspected or known coronary artery disease (CAD) who underwent CCTA with a 320-row scanner. The patients were randomly divided into dynamic and standard CCTA groups, and the CT dose index (CTDIvol) and dose length product (DLP) calculated by the CT system were compared between the two protocols and with the latest DRL.
Standard and dynamic CCTA scans were performed in 77 and 87 patients, respectively. CTDIvol was significantly higher for standard CCTA than for dynamic CCTA (41 ± 35 mGy vs. 22 ± 7 mGy, p = 0.0014). DLP was also significantly higher for standard CCTA than for dynamic CCTA (864 ± 702 mGy × cm vs. 434 ± 106 mGy × cm, p < .0001). For standard scans, CTDIvol and DLP exceeded the 2020 DRL in Japan in 16% (12/77) and 17% (13/77) of cases, respectively. In contrast, rates for the dynamic scan were only 1% (1/87) for CTDIvol and 0% (0/87) for DLP.
The dose of radiation exposure during dynamic CCTA with a 320-row scanner does not exceed that of standard CCTA and is sufficient to meet the latest DRL. Thus, our results suggest that the method is safe from the perspective of radiation exposure.
能在一次旋转中覆盖整个心脏的 320 排探测器 CT 扫描仪,有助于降低心电图门控冠状动脉 CT 血管造影术(CCTA)中的辐射暴露。最近,研究人员提出了使用 320 排扫描仪进行剂量调制的动态 CCTA,用于检测功能性心肌缺血。在本研究中,我们比较并验证了这种方法的辐射剂量与标准 CCTA 方法和最新诊断参考水平(DRL)的辐射剂量。
这项研究共纳入了 164 例连续疑似或已知冠心病(CAD)患者,他们使用 320 排扫描仪进行了 CCTA。患者被随机分为动态和标准 CCTA 组,比较了两种方案和最新 DRL 之间的 CT 剂量指数(CTDIvol)和 CT 系统计算的剂量长度乘积(DLP)。
标准和动态 CCTA 扫描分别在 77 例和 87 例患者中进行。标准 CCTA 的 CTDIvol 明显高于动态 CCTA(41±35mGy 比 22±7mGy,p=0.0014)。标准 CCTA 的 DLP 也明显高于动态 CCTA(864±702mGy×cm 比 434±106mGy×cm,p<0.0001)。对于标准扫描,CTDIvol 和 DLP 分别有 16%(12/77)和 17%(13/77)的病例超过了日本 2020 年的 DRL。相比之下,动态扫描的 CTDIvol 和 DLP 仅分别有 1%(1/87)和 0%(0/87)的病例超过了 DRL。
使用 320 排扫描仪进行动态 CCTA 的辐射暴露剂量不超过标准 CCTA,足以满足最新的 DRL。因此,从辐射暴露的角度来看,我们的结果表明该方法是安全的。