• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

甲状旁腺癌——氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描上代谢性骨骼超级扫描的恶性病因

Parathyroid Carcinoma - A Malignant Cause of Metabolic Skeletal Super Scan on Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography.

作者信息

Sampath Santhosh, Jeeva Godwin

机构信息

Division of PET/CT, Gemini Scans, Chennai, Tamil Nadu, India.

出版信息

Indian J Nucl Med. 2021 Apr-Jun;36(2):223-225. doi: 10.4103/ijnm.ijnm_213_20. Epub 2021 Jun 21.

DOI:10.4103/ijnm.ijnm_213_20
PMID:34385804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8320830/
Abstract

Excessive abnormal tracer uptake in active tracer avid organ(s) with the suppression of physiological background tracer distribution is termed as super scan. Herein, we present an F-fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET/CT), where the metabolic pattern of skeletal super scan with coexistent parathyroid tumor was seen giving rise to the suspicion of primary hyperparathyroidism. It was subsequently diagnosed as a case of parathyroid carcinoma. Very high levels of serum parathormone in parathyroid carcinoma lead to accelerated bone turn over resulting in metabolic skeletal superscan in FDG-PET/CT which is seldom observed in parathyroid adenoma.

摘要

在放射性示踪剂摄取活跃的器官中出现过量异常示踪剂摄取，同时生理性背景示踪剂分布受到抑制，这种情况被称为超级骨显像。在此，我们展示了一例氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描（FDG-PET/CT），其中观察到骨骼超级骨显像的代谢模式与甲状旁腺肿瘤并存，这引发了对原发性甲状旁腺功能亢进的怀疑。随后该病例被诊断为甲状旁腺癌。甲状旁腺癌中血清甲状旁腺激素水平极高，导致骨转换加速，从而在FDG-PET/CT中出现代谢性骨骼超级骨显像，而这种情况在甲状旁腺腺瘤中很少见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a390/8320830/dbf402cf7cd9/IJNM-36-223-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a390/8320830/f808bfa87575/IJNM-36-223-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a390/8320830/8a0f40a82c02/IJNM-36-223-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a390/8320830/dbf402cf7cd9/IJNM-36-223-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a390/8320830/f808bfa87575/IJNM-36-223-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a390/8320830/8a0f40a82c02/IJNM-36-223-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a390/8320830/dbf402cf7cd9/IJNM-36-223-g003.jpg

相似文献

1
Parathyroid Carcinoma - A Malignant Cause of Metabolic Skeletal Super Scan on Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography.甲状旁腺癌——氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描上代谢性骨骼超级扫描的恶性病因
Indian J Nucl Med. 2021 Apr-Jun;36(2):223-225. doi: 10.4103/ijnm.ijnm_213_20. Epub 2021 Jun 21.
2
Complimentary Role of [18F]FDG and [18F]NaF-PET/CT in Evaluating Synchronous Thyroid Carcinoma and Parathyroid Adenoma with Brown Tumors.[18F]氟代脱氧葡萄糖（[18F]FDG）和[18F]氟化钠（[18F]NaF）正电子发射断层扫描/计算机断层扫描（PET/CT）在评估伴有棕色瘤的同步性甲状腺癌和甲状旁腺腺瘤中的互补作用
World J Nucl Med. 2024 Jun 14;23(3):220-224. doi: 10.1055/s-0044-1787732. eCollection 2024 Sep.
3
Super Scan Caused by Parathyroid Carcinoma Observed Both inF-FDG PET/CT Scan and Tc-99m MDP Bone Scintigraphy.甲状旁腺癌导致的超级扫描在F-FDG PET/CT扫描和Tc-99m MDP骨闪烁显像中均有观察到。
Mol Imaging Radionucl Ther. 2017 Oct 3;26(3):116-119. doi: 10.4274/mirt.70188.
4
Differential diagnosis between secondary and tertiary hyperparathyroidism in a case of a giant-cell and brown tumor containing mass. Findings by (99m)Tc-MDP, (18)F-FDG PET/CT and (99m)Tc-MIBI scans.一例含巨细胞瘤和棕色瘤肿块患者继发性与三发性甲状旁腺功能亢进的鉴别诊断。（99m）锝-亚甲基二膦酸盐、（18）氟-脱氧葡萄糖正电子发射断层显像/X线计算机体层成像及（99m）锝-甲氧基异丁基异腈扫描结果
Hell J Nucl Med. 2014 Sep-Dec;17(3):214-7. doi: 10.1967/s002449910147. Epub 2014 Nov 12.
5
F-18 fluorodeoxyglucose positron emission tomography "super scan" in a patient of metastatic primitive neuroectodermal tumor of the kidney.一名肾转移性原始神经外胚层肿瘤患者的F-18氟脱氧葡萄糖正电子发射断层扫描“超级扫描”
Indian J Nucl Med. 2012 Apr;27(2):115-8. doi: 10.4103/0972-3919.110709.
6
More advantages in detecting bone and soft tissue metastases from prostate cancer using F-PSMA PET/CT.使用F-PSMA PET/CT检测前列腺癌骨和软组织转移方面有更多优势。
Hell J Nucl Med. 2019 Jan-Apr;22(1):6-9. doi: 10.1967/s002449910952. Epub 2019 Mar 7.
7
Positron emission tomography/computed tomography imaging of brown tumors mimicking multiple skeletal metastases in patient with primary hyperparathyroidism.原发性甲状旁腺功能亢进患者中，棕色瘤正电子发射断层扫描/计算机断层扫描成像表现酷似多发性骨转移。
Indian J Endocrinol Metab. 2012 Sep;16(5):850-2. doi: 10.4103/2230-8210.100682.
8
Isolated Splenic Tuberculosis Masquerading as Disease Progression of Hodgkin's Lymphoma on InterimF-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Scan.孤立性脾结核在中期氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描中伪装成霍奇金淋巴瘤的疾病进展
Indian J Nucl Med. 2021 Jan-Mar;36(1):100-102. doi: 10.4103/ijnm.IJNM_145_20. Epub 2021 Mar 4.
9
Metabolic Superscan on 18 F-FDG PET/CT in a Patient With Secondary Hyperparathyroidism.18 F-FDG PET/CT 代谢全身扫描在继发性甲状旁腺功能亢进患者中的应用。
Clin Nucl Med. 2024 Jan 1;49(1):e19-e21. doi: 10.1097/RLU.0000000000004941. Epub 2023 Oct 25.
10
Bone metastasis versus bone marrow metastasis? Integration of diagnosis by (18)F-fluorodeoxyglucose positron emission/computed tomography in advanced malignancy with super bone scan: two case reports and literature review.骨转移与骨髓转移？（18）F-氟脱氧葡萄糖正电子发射/计算机断层扫描在高级恶性肿瘤中超骨扫描的诊断整合：两例报告及文献复习。
Kaohsiung J Med Sci. 2013 Apr;29(4):229-33. doi: 10.1016/j.kjms.2012.08.038. Epub 2012 Nov 29.

引用本文的文献

1
Case report: F-FDG PET/CT skeletal superscan-like in an adult patient with acute lymphoblastic leukemia.病例报告：一名成年急性淋巴细胞白血病患者出现类似F-FDG PET/CT全身骨骼扫描表现。
Front Oncol. 2024 Jul 15;14:1401453. doi: 10.3389/fonc.2024.1401453. eCollection 2024.

本文引用的文献

1
Super Scan Caused by Parathyroid Carcinoma Observed Both inF-FDG PET/CT Scan and Tc-99m MDP Bone Scintigraphy.甲状旁腺癌导致的超级扫描在F-FDG PET/CT扫描和Tc-99m MDP骨闪烁显像中均有观察到。
Mol Imaging Radionucl Ther. 2017 Oct 3;26(3):116-119. doi: 10.4274/mirt.70188.
2
18F-FDG PET/CT Osteometabolic Activity in Metastatic Parathyroid Carcinoma.18F-FDG PET/CT 检测转移性甲状旁腺癌的代谢活性。
Clin Nucl Med. 2016 Sep;41(9):724-5. doi: 10.1097/RLU.0000000000001278.
3
Brown Tumors Due to Primary Hyperparathyroidism in a Patient with Parathyroid Carcinoma Mimicking Skeletal Metastases on (18)F-FDG PET/CT.
甲状旁腺癌患者的原发性甲状旁腺功能亢进棕色瘤：（18）F-FDG PET/CT 上酷似骨骼转移
Diagnostics (Basel). 2015 Jul 9;5(3):290-3. doi: 10.3390/diagnostics5030290.
4
Metabolic Skeletal Superscan on 18F-FDG PET/CT in a Case of Acute Lymphoblastic Leukemia.18F-FDG PET/CT 代谢性骨骼全身扫描在急性淋巴细胞白血病中的应用
Clin Nucl Med. 2015 Jul;40(7):567-8. doi: 10.1097/RLU.0000000000000785.
5
18F-FDG PET/CT superscan in prostate cancer.18F-FDG PET/CT 全身扫描在前列腺癌中的应用。
Clin Nucl Med. 2014 Oct;39(10):912-4. doi: 10.1097/RLU.0000000000000376.
6
FDG-anorectic parathyroid carcinoma with FDG-avid bone metastasis on PET/CT images.FDG 抑制型甲状旁腺癌伴 FDG 摄取的骨转移，PET/CT 图像可见。
Clin Nucl Med. 2013 Nov;38(11):916-8. doi: 10.1097/RLU.0b013e3182a757fd.
7
¹⁸F-FDG PET findings of a parathyroid cancer with cortical skeletal demineralization.
Clin Nucl Med. 2012 Mar;37(3):293-5. doi: 10.1097/RLU.0b013e3182443fb1.
8
Incidence and prognosis of parathyroid gland carcinoma: a population-based study in The Netherlands estimating the preoperative diagnosis.甲状旁腺癌的发病率和预后：荷兰基于人群的研究，估计术前诊断。
Am J Surg. 2011 Nov;202(5):590-7. doi: 10.1016/j.amjsurg.2010.09.025. Epub 2011 Aug 20.
9
F-18 FDG PET superscan.
Clin Nucl Med. 2006 Jan;31(1):28-9. doi: 10.1097/01.rlu.0000191569.37542.3d.