Department of Psychiatry, The Psychiatric Institute, College of Medicine, University of Illinois Chicago (UIC), 1601 West Taylor Street, Chicago, IL, 60612, USA.
Inflamm Res. 2021 Sep;70(9):935-937. doi: 10.1007/s00011-021-01491-w. Epub 2021 Aug 14.
We report a case of itchy papulovesicular rash consistent with varicella-zoster virus reactivation after Pfizer-BioNTech vaccine second dose administration. While there have been cases of varicella-zoster virus reactivation due to COVID-19 or COVID-19 vaccine inoculation in older individuals with pre-existing conditions, this case report describes the first case of varicella-zoster virus reactivation on a healthy, young male in the absence of pre-existing conditions. The mechanisms underlying varicella-zoster virus reactivation in patients with COVID-19 are unknown and should be further characterized.
我们报告了一例 Pfizer-BioNTech 疫苗第二剂接种后出现瘙痒性丘疱疹样皮疹，符合水痘带状疱疹病毒再激活。虽然在有基础疾病的老年个体中，由于 COVID-19 或 COVID-19 疫苗接种，已经有过水痘带状疱疹病毒再激活的病例，但本病例报告描述了首例无基础疾病的健康年轻男性中，水痘带状疱疹病毒在 COVID-19 患者中再激活的机制尚不清楚，应进一步研究。
