Universidad Autónoma de Querétaro, Facultad de Medicina. Laboratorio Multidisciplinario de, Investigación Biomédica Avanzada. Querétaro, México.
Instituto de Neurobiología UNAM, Campus Juriquilla, Querétaro, México.
Psychiatry Res. 2021 Oct;304:114151. doi: 10.1016/j.psychres.2021.114151. Epub 2021 Aug 2.
Mild cognitive impairment (MCI) is a state between normal cognition and dementia. Currently, there is little evidence of repetitive Transcranial Magnetic Stimulation (rTMS) as an enhancing tool for Cognitive Stimulation (CS) on MCI. The importance of this study consists in its assessment of the enhancing effect of rTMS on CS in 22 MCI patients randomized and divided into two group: active (AG) and sham (SG). Diagnoses and assessments were determined during 30 sessions over a 10-week period by Montreal Cognitive Assessment (MoCA) and Neuropsí test. Results were statistically significant in the intergroup analysis with MoCA and intragroup only for AG.
轻度认知障碍（MCI）是介于正常认知和痴呆之间的一种状态。目前，重复经颅磁刺激（rTMS）作为认知刺激（CS）增强工具在 MCI 中的应用证据较少。本研究的重要性在于评估 rTMS 对 22 例 MCI 患者 CS 的增强作用，这些患者随机分为两组：主动组（AG）和假刺激组（SG）。在 10 周的 30 次治疗过程中，通过蒙特利尔认知评估（MoCA）和神经心理学测试进行诊断和评估。结果在 MoCA 的组间分析和仅在 AG 的组内分析中具有统计学意义。
