Balaja Warren R, Jacob Sarah, Hamidpour Soheila, Masoud Amgad
Internal Medicine, University of Missouri Kansas City School of Medicine, Kansas City, USA.
Pathology, University of Missouri Kansas City School of Medicine, Kansas City, USA.
Cureus. 2021 Jul 13;13(7):e16359. doi: 10.7759/cureus.16359. eCollection 2021 Jul.
As the coronavirus pandemic continues to evolve, so does the understanding of different presentations of disease. In this case report, we describe a patient whose presentation of COVID-19 was with acute icteric hepatitis without respiratory symptoms. This is the first case in the literature to our knowledge to report jaundice as the initial presentation of disease and adds to just a handful of cases in the literature of acute hepatitis as the sole presentation of COVID-19. Additionally, despite severe hepatitis, the patient had a benign course of COVID-19 and did not require aggressive medical care; this strays from conventional paradigms that associate severity of COVID-19 with a degree of aminotransferase elevation. The purpose of this report is to make physicians aware of acute icteric hepatitis as a presentation of COVID-19 infection and to facilitate discussion and further research in the area of COVID-19-induced hepatitis.
随着新冠病毒疫情不断演变，人们对该疾病不同表现形式的认识也在不断深化。在本病例报告中，我们描述了一名新冠肺炎患者，其表现为急性黄疸型肝炎且无呼吸道症状。据我们所知，这是文献中首例将黄疸作为疾病初始表现的病例，也为文献中仅有的少数以急性肝炎作为新冠肺炎唯一表现的病例增添了新案例。此外，尽管该患者患有严重肝炎，但其新冠肺炎病程呈良性，无需积极的医疗救治；这与将新冠肺炎的严重程度与转氨酶升高程度相关联的传统模式不同。本报告的目的是让医生们认识到急性黄疸型肝炎可作为新冠病毒感染的一种表现形式，并促进在新冠病毒诱发肝炎领域的讨论和进一步研究。
