Minneapolis VA Health Care Center, Minneapolis.
J Nerv Ment Dis. 2021 Aug 1;209(8):592-599. doi: 10.1097/NMD.0000000000001351.
Objectives consist of updating published reports on the recognition, assessment, and care of patients with Wernicke-Korsakoff syndrome (WKS). Methods included defining relevant terms, describing core clinical phenomena, conducting meaningful reviews for latter-day WKS publications, and selecting instructive case examples. Findings covered epidemiology, precipitants, neuroimaging studies, alternate learning strategies in WKS, adjunctive treatments, and promising research. In conclusion, patients, their family members, clinicians, and public health experts should benefit from this updated knowledge. Countries with substantial alcohol consumption should consider emulating Holland in designating WKS research centers, founding regional clinical facilities, and funding multidisciplinary expert teams.
目的包括更新关于韦尼克-科尔萨科夫综合征(WKS)患者的识别、评估和护理的已发表报告。方法包括定义相关术语、描述核心临床现象、对 WKS 后期出版物进行有意义的综述以及选择有启发性的病例示例。研究结果涵盖流行病学、诱发因素、神经影像学研究、WKS 中的替代学习策略、辅助治疗以及有前途的研究。总之,患者、他们的家庭成员、临床医生和公共卫生专家应该从这些最新知识中受益。酒精消耗量大的国家应该考虑效仿荷兰,指定 WKS 研究中心、建立区域临床设施和资助多学科专家团队。