Brown Devin L, Cowdery Joan E
Stroke Program, University of Michigan, Ann Arbor, Michigan, USA.
School of Health Promotion and Human Performance, Eastern Michigan University, Ypsilanti, Michigan, USA.
J Am Coll Health. 2023 Aug-Sep;71(6):1643-1645. doi: 10.1080/07448481.2021.1947840. Epub 2021 Aug 16.
We examined clinical trial knowledge and attitudes, and their relationship with willingness to participate in COVID-19 vaccine trials, and willingness to accept a COVID-19 vaccine among college students.
331 undergraduates: mean age 25; 72% women; and 78% white.
We administered an online, anonymous survey to undergraduate students in July, 2020, during the COVID-19 pandemic.
The mean clinical trial knowledge score was 65% (SD = 16) correct. The mean attitudes toward clinical trials score (1 most negative: 5 most positive) was 3.3 (SD = 0.5). Attitudes toward clinical trials were associated with likelihood of COVID-19 trial participation (positive 76% vs. negative 35%, = 0.001) and a trend toward likelihood of accepting a COVID-19 vaccine if available (positive 89% vs. negative 67%, = 0.066).
General clinical trial knowledge and attitudes appear to be important targets for educational interventions. Furthermore, fostering positive attitudes may lead to improved COVID-19 trial participation and vaccine uptake.
我们研究了大学生对临床试验的知识和态度，以及它们与参与新冠疫苗试验意愿和接受新冠疫苗意愿之间的关系。
331名本科生，平均年龄25岁；72%为女性；78%为白人。
在2020年7月新冠疫情期间，我们对本科生进行了一项在线匿名调查。
临床试验知识的平均得分正确率为65%（标准差=16）。对临床试验态度的平均得分（1分为最负面：5分为最正面）为3.3（标准差=0.5）。对临床试验的态度与参与新冠试验的可能性相关（积极态度者为76%，消极态度者为35%，P=0.001），并且如果有新冠疫苗，接受疫苗的可能性有一定趋势（积极态度者为89%，消极态度者为67%，P=0.066）。
一般的临床试验知识和态度似乎是教育干预的重要目标。此外，培养积极态度可能会提高参与新冠试验的比例和疫苗接种率。
