Tersalvi Gregorio, Gasperetti Alessio, Schiavone Marco, Dauw Jeroen, Gobbi Cecilia, Denora Marialessia, Krul Joel Daniel, Cioffi Giacomo Maria, Mitacchione Gianfranco, Forleo Giovanni B
Department of Internal Medicine, Hirslanden Klinik St. Anna, Lucerne, Switzerland.
Cardiology Unit, ASST-Fatebenefratelli Sacco, Luigi Sacco University Hospital, Milan, Italy.
J Geriatr Cardiol. 2021 Jul 28;18(7):560-576. doi: 10.11909/j.issn.1671-5411.2021.07.004.
Acute heart failure (AHF) is a major cause of unplanned hospitalisations in the elderly and is associated with high mortality. Its prevalence has grown in the last years due to population aging and longer life expectancy of chronic heart failure patients. Although international societies have provided guidelines for the management of AHF in the general population, scientific evidence for geriatric patients is often lacking, as these are underrepresented in clinical trials. Elderly have a different risk profile with more comorbidities, disability, and frailty, leading to increased morbidity, longer recovery time, higher readmission rates, and higher mortality. Furthermore, therapeutic options are often limited, due to unfeasibility of invasive strategies, mechanical circulatory support and cardiac transplantation. Thus, the in-hospital management of AHF should be tailored to each patient's clinical situation, cardiopulmonary condition and geriatric assessment. Palliative care should be considered in some cases, in order to avoid unnecessary diagnostics and/or treatments. After discharge, a strict follow-up through outpatient clinic or telemedicine is can improve quality of life and reduce rehospitalisation rates. The aim of this review is to offer an insight on current literature and provide a clinically oriented, patient-tailored approach regarding assessment, treatment and follow-up of elderly patients admitted for AHF.
急性心力衰竭(AHF)是老年人计划外住院的主要原因,且与高死亡率相关。由于人口老龄化和慢性心力衰竭患者预期寿命延长,其患病率在过去几年有所上升。尽管国际社会已为普通人群的AHF管理提供了指南,但老年患者的科学证据往往不足,因为他们在临床试验中的代表性不足。老年人具有不同的风险特征,合并症、残疾和虚弱更多,导致发病率增加、恢复时间延长、再入院率升高和死亡率更高。此外,由于侵入性策略、机械循环支持和心脏移植不可行,治疗选择往往有限。因此,AHF的院内管理应根据每位患者的临床情况、心肺状况和老年评估进行调整。在某些情况下应考虑姑息治疗,以避免不必要的诊断和/或治疗。出院后,通过门诊或远程医疗进行严格随访可以改善生活质量并降低再住院率。本综述的目的是深入了解当前文献,并针对因AHF入院的老年患者的评估、治疗和随访提供以临床为导向、针对患者的方法。