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老年人群接触性致敏的最新情况

Update on Contact Sensitization in the Older Adult Population.

作者信息

Woodruff Carina M, Kollhoff Alexander, Butler Daniel C, Botto Nina

机构信息

From the Department of Dermatology, University of California San Francisco.

Medical College of Georgia, August, GA.

出版信息

Dermatitis. 2022;33(2):122-128. doi: 10.1097/DER.0000000000000763.

Abstract

BACKGROUND

Little is known about the epidemiology of allergic contact dermatitis in the aging US population.

OBJECTIVE

The aim of this study was to describe patch test results in a cohort of older adult patients evaluated in a patch testing clinic in a tertiary medical center.

METHODS

This study was a retrospective analysis of patch test results of adults 65 years and older from February 2013 to December 2019.

RESULTS

Data from a total of 169 patients 65 years and older were analyzed. Of these patients, 84.6% (143/169) had 1 or more positive reactions on patch testing, 84.6% (121/143) of which were felt to be clinically relevant and received a final diagnosis of allergic contact dermatitis. The most common allergen categories were fragrances (30.1%), preservatives (20.8%), metals (11.0%), medicaments (8.3%), and textile dyes (6.5%). The most common individual allergens were Myroxylon pereirae resin (balsam of Peru), hydroperoxide of linalool, methylisothiazolinone, nickel sulfate, and fragrance mix I. Personal products were by far the most common presumed source of allergen exposure.

CONCLUSIONS

Allergic contact dermatitis is a common diagnosis in the older adult population, and patch testing with allergen avoidance counseling can be an important diagnostic step and potential cure for this allergic condition.

摘要

背景

在美国老年人群中,过敏性接触性皮炎的流行病学情况鲜为人知。

目的

本研究旨在描述在一家三级医疗中心的斑贴试验诊所接受评估的老年患者队列的斑贴试验结果。

方法

本研究是对2013年2月至2019年12月期间65岁及以上成年人的斑贴试验结果进行的回顾性分析。

结果

共分析了169例65岁及以上患者的数据。在这些患者中,84.6%(143/169)在斑贴试验中有1种或更多阳性反应,其中84.6%(121/143)被认为具有临床相关性,并最终诊断为过敏性接触性皮炎。最常见的过敏原类别为香料(30.1%)、防腐剂(20.8%)、金属(11.0%)、药物(8.3%)和纺织染料(6.5%)。最常见的单一过敏原为秘鲁香脂(秘鲁胶树脂)、芳樟醇过氧化氢、甲基异噻唑啉酮、硫酸镍和香料混合物I。个人护理产品是迄今为止最常见的推测过敏原暴露源。

结论

过敏性接触性皮炎在老年人群中是一种常见诊断,进行斑贴试验并提供避免接触过敏原的咨询可能是这一过敏病症的重要诊断步骤及潜在治疗方法。

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