Li Junfei, Shen Chen, Huang Tony Jun, Cummer Steven A
Department of Electrical and Computer Engineering, Duke University, Durham, NC 27708, USA.
Department of Mechanical Engineering, Rowan University, Glassboro, NJ 08028, USA.
Sci Adv. 2021 Aug 18;7(34). doi: 10.1126/sciadv.abi5502. Print 2021 Aug.
Acoustic tweezers use ultrasound for contact-free, bio-compatible, and precise manipulation of particles from millimeter to submicrometer scale. In microfluidics, acoustic tweezers typically use an array of sources to create standing wave patterns that can trap and move objects in ways constrained by the limited complexity of the acoustic wave field. Here, we demonstrate spatially complex particle trapping and manipulation inside a boundary-free chamber using a single pair of sources and an engineered structure outside the chamber that we call a shadow waveguide. The shadow waveguide creates a tightly confined, spatially complex acoustic field inside the chamber without requiring any interior structure that would interfere with net flow or transport. Altering the input signals to the two sources creates trapped particle motion along an arbitrary path defined by the shadow waveguide. Particle trapping, particle manipulation and transport, and Thouless pumping are experimentally demonstrated.
声镊利用超声波对毫米至亚微米尺度的粒子进行非接触、生物兼容且精确的操控。在微流控领域,声镊通常使用一系列声源来创建驻波模式,这种模式能够以受声波场有限复杂性限制的方式捕获和移动物体。在此,我们展示了在无边界腔室内使用一对声源以及腔室外一个我们称为“阴影波导”的工程结构进行空间复杂的粒子捕获和操控。阴影波导在腔室内创建了一个紧密受限、空间复杂的声场,而无需任何会干扰净流或传输的内部结构。改变输入到两个声源的信号会使捕获的粒子沿着由阴影波导定义的任意路径运动。通过实验证明了粒子捕获、粒子操控与传输以及 Thouless 泵浦现象。