Baudoin Michael, Gerbedoen Jean-Claude, Riaud Antoine, Matar Olivier Bou, Smagin Nikolay, Thomas Jean-Louis
Université de Lille, CNRS, Centrale Lille, ISEN, Université Polytechnique des Hauts-de-France, UMR 8520, SATT Nord, IEMN, International laboratory LIA/LICS, F-59000 Lille, France.
Université Paris Sorbonne Cité, INSERM UMR-S1147, 45 Rue des Saints Pères, 75270 Paris, France.
Sci Adv. 2019 Apr 12;5(4):eaav1967. doi: 10.1126/sciadv.aav1967. eCollection 2019 Apr.
Acoustical tweezers based on focalized acoustical vortices hold the promise of precise contactless manipulation of millimeter down to submicrometer particles, microorganisms, and cells with unprecedented combined selectivity and trapping force. Yet, the widespread dissemination of this technology has been hindered by severe limitations of current systems in terms of performance and/or miniaturization and integrability. Here, we unleash the potential of focalized acoustical vortices by developing the first flat, compact, paired single electrode focalized acoustical tweezers. These tweezers rely on spiraling transducers obtained by folding a spherical acoustical vortex on a flat piezoelectric substrate. We demonstrate the ability of these tweezers to grab and displace micrometric objects in a standard microfluidic environment with unique selectivity. The simplicity of this system and its scalability to higher frequencies open tremendous perspectives in microbiology, microrobotics, and microscopy.
基于聚焦声涡的声学镊子有望对从毫米级到亚微米级的颗粒、微生物和细胞进行精确的非接触式操控，其选择性和捕获力的组合堪称空前。然而，目前该技术在性能和/或小型化及可集成性方面存在严重局限，阻碍了它的广泛应用。在此，我们通过开发首个扁平、紧凑的配对单电极聚焦声学镊子，释放了聚焦声涡的潜力。这些镊子依赖于通过在扁平压电基板上折叠球形声涡而获得的螺旋换能器。我们展示了这些镊子在标准微流体环境中以独特的选择性抓取和移动微米级物体的能力。该系统的简单性及其向更高频率扩展的能力，为微生物学、微型机器人技术和显微镜技术开辟了广阔的前景。
