Department of Poultry Diseases, National Veterinary Research Institute, Pulawy, Poland.
PLoS One. 2021 Aug 19;16(8):e0256137. doi: 10.1371/journal.pone.0256137. eCollection 2021.
Inclusion body hepatitis (IBH) is, in some cases, a fatal disease affecting fowl by adenovirus strains which are subdivided into 5 species (A-E). In the current study, we investigated sequences from the Loop L1 region of the hexon gene of sequences of adenovirus field stains 1/A and 11/D isolated from a poultry flock co-infected with IBH and avian reoviruses ARVs. In early 2021, an epidemiologic survey highlighted the coinfection adenoviruses with other viruses (orthoreovirus infection) as being particularly deleterious within the poultry industry. Here, we investigated the Loop L1 HVR1-4 region of the hexon gene with relative synonymous codon usage (RSCU) designation and RSCU inclusive of all the mutations. These are the first results that have been presented on fowl adenovirus species A and D with simultaneous reovirus infection in 38-days old broiler chickens in Poland.
包涵体肝炎（IBH）在某些情况下是一种致命疾病，由腺病毒株引起，这些病毒株分为 5 个种（A-E）。在当前的研究中，我们研究了来自感染包涵体肝炎和禽呼肠孤病毒（ARV）的家禽群中的腺病毒田间株 1/A 和 11/D 的六邻体基因环 L1 区的序列。2021 年初，一项流行病学调查强调了腺病毒与其他病毒（正呼肠孤病毒感染）的共同感染在禽业中特别有害。在这里，我们研究了六邻体基因的环 L1 HVR1-4 区，并用相对同义密码子使用（RSCU）指定和包含所有突变的 RSCU 进行了研究。这些是在波兰 38 日龄肉鸡中同时感染禽呼肠孤病毒的情况下，首次报告的家禽腺病毒 A 和 D 种的结果。
