Kaur Arshpreet, Tiwari Ruchi, Tiwari Gaurav, Ramachandran Vadivelan
Institute of Pharmacy, Pranveer Singh Institute of Technology, Bhauti, Kanpur, Uttar Pradesh, India.
Department of Pharmacology, JSS College of Pharmacy, JSS Academy of Higher Education & Research, Ooty, Nilgiris, Tamil Nadu, India.
Drug Res (Stuttg). 2022 Jan;72(1):5-17. doi: 10.1055/a-1555-2919. Epub 2021 Aug 19.
Resveratrol (RSV), the most effective stilbene phytoalexin synthesized naturally or induced in plants as part of their defense mechanism, is a key component of natural phenolic compounds and is being considered as a treatment option for a variety of diseases. RSV was discovered in the skin of red grapes, mulberries, peanuts, pines, and weed root extracts. It was first extracted from white hellebore () roots in 1940, then from roots in 1963. However, RSV's use as a drug is limited due to its initial conformational strength and poor stability. The research focused on a set of RSV biological activity data. RSV has been the subject of growing concern, despite its wide range of biological and therapeutic applications. According to the literature, RSV has antioxidant, anti-cancer, cardioprotective, neuroprotective, anti- inflammatory, anti-microbial, immunomodulatory, and radioprotective properties. The current analysis summarized biological applications of RSV, their mechanisms of action, and recent scientific development in the area of their delivery. It is possible to infer that RSV has many effects on infected cells' cellular functions.
白藜芦醇（RSV）是植物自然合成或诱导产生的最有效的芪类植保素，作为植物防御机制的一部分，它是天然酚类化合物的关键成分，正被视为多种疾病的一种治疗选择。RSV在红葡萄皮、桑椹、花生、松树和杂草根提取物中被发现。它于1940年首次从白藜芦（）根中提取，然后在1963年从根中提取。然而，由于其初始构象强度和稳定性差，RSV作为药物的应用受到限制。该研究聚焦于一组RSV的生物活性数据。尽管RSV有广泛的生物学和治疗应用，但它一直是越来越受关注的对象。根据文献，RSV具有抗氧化、抗癌、心脏保护、神经保护、抗炎、抗微生物、免疫调节和辐射防护特性。当前的分析总结了RSV的生物学应用、其作用机制以及该领域在其递送方面的最新科学进展。可以推断，RSV对受感染细胞的细胞功能有许多影响。
