Hillen Barlo, Simon Perikles, Schlotter Sebastian, Nitsche Oliver, Bähner Viola, Poplawska Krystyna, Pfirrmann Daniel
Department of Sports Medicine, Disease Prevention and Rehabilitation, Johannes Gutenberg University, Mainz, Germany.
Medical Department of Pediatrics Pulmonology, Allergology and Cystic Fibrosis, University Medical Centre, Langenbeckstraße 1, 55131, Mainz, Germany.
BMC Sports Sci Med Rehabil. 2021 Aug 19;13(1):95. doi: 10.1186/s13102-021-00323-y.
Regular participation in exercise is important for people with cystic fibrosis (CF). Therefore, we implemented a personalized, web-based exercise intervention over the course of one year for people with CF. The aims were to investigate the feasibility of the intervention and to evaluate changes in exercise participation, lung function, and exercise capacity.
In total, 11/17 participants [aged 12-52 years; FEV%pred. 72.3 (SD: 17.3)] were included in the final data analysis. Every week, the participants received an individual training recommendation at the start and uploaded their training report on our website at the end of each week. The number of training minutes and sessions performed were analyzed over 13 four-week training sections. The participation in exercise (physical activity questionnaire), lung function and exercise capacity were assessed at baseline (T0), after 12 weeks (T1) and after 52 weeks (T2).
A training duration of 178 min (SD: 75.5) and 3.3 (SD: 0.89) training sessions could be achieved weekly. In the first four-week training section, the participants performed 137.31 (SD: 95.7) minutes of training, with an increase of 42% in the third training section (195.01, SD: 134.99). Minutes of training reported on the questionnaire increased by 39.7% from T0 (179.38 min, SD: 120.9) to T1 (250.63 min, SD: 124.1) but decreased at T2 (166.88, SD: 155.4). There were slight decreases in lung function (FEV - 3.9%pred.; FVC - 1.9%pred.) and slight increases in exercise capacity (VO + 1.5 ml/min/kg; six-minute-walk-test-distance + 26 m). Noticeably, five participants experienced deteriorations in their FEV of more than 5% but simultaneously experienced improvements in the parameters of exercise capacity of more than 5% throughout the year.
The web-based concept was feasible for the participants over the course of a year and supported exercise participation. The improvement in exercise capacity due to increased exercise participation over a prolonged period of time, despite a decrease in lung function, should be further investigated. Finally, if integrated into usual care, this approach could facilitate the prescription of regular personalized exercise and promote exercise participation in the daily lives of people with CF.
定期参加体育锻炼对囊性纤维化（CF）患者很重要。因此，我们在一年的时间里为CF患者实施了一项基于网络的个性化运动干预。目的是调查该干预措施的可行性，并评估运动参与度、肺功能和运动能力的变化。
最终数据分析纳入了11/17名参与者[年龄12 - 52岁；预测第一秒用力呼气容积（FEV）百分比为72.3（标准差：17.3）]。参与者每周开始时会收到个性化的训练建议，并在每周结束时在我们的网站上上传他们的训练报告。在13个为期四周的训练阶段中分析了训练分钟数和训练次数。在基线（T0）、12周后（T1）和52周后（T2）评估运动参与情况（体力活动问卷）、肺功能和运动能力。
每周可实现178分钟（标准差：75.5）的训练时长和3.3次（标准差：0.89）的训练次数。在第一个为期四周的训练阶段，参与者进行了137.31分钟（标准差：95.7）的训练，在第三个训练阶段增加了42%（195.01，标准差：134.99）。问卷中报告的训练分钟数从T0（179.38分钟，标准差：120.9）到T1（250.63分钟，标准差：124.1）增加了39.7%，但在T2时有所下降（166.88，标准差：155.4）。肺功能略有下降（预测FEV下降3.9%；预测用力肺活量下降1.9%），运动能力略有提高（每公斤体重每分钟摄氧量增加1.5毫升；六分钟步行试验距离增加26米）。值得注意的是，五名参与者的FEV下降超过5%，但同时全年运动能力参数提高超过5%。
基于网络的理念在一年时间里对参与者是可行的，并支持了运动参与。尽管肺功能下降，但长期运动参与导致的运动能力提高值得进一步研究。最后，如果纳入常规护理，这种方法可以促进定期个性化运动的处方，并促进CF患者在日常生活中的运动参与。
