• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

两名患者在接种 BNT162b2 mRNA COVID-19 疫苗后出现暴发性心肌炎和全身炎症反应。

Fulminant myocarditis and systemic hyperinflammation temporally associated with BNT162b2 mRNA COVID-19 vaccination in two patients.

机构信息

Division of Cardiology, Virginia Commonwealth University, Richmond, VA, United States of America.

Allergy, Immunology and Rheumatology, Virginia Commonwealth University, Richmond, VA, United States of America.

出版信息

Int J Cardiol. 2021 Oct 1;340:119-121. doi: 10.1016/j.ijcard.2021.08.018. Epub 2021 Aug 18.

DOI:10.1016/j.ijcard.2021.08.018
PMID:34416319
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8372420/
Abstract

Immune-mediated myocardial injury following Severe Acute Respiratory Syndrome Coronavirys-2 (SARS-CoV2) infection has been described in adults and children. Cases of myocarditis following immunization for SARS-CoV2 have recently been documented, mostly associated with mild severity and spontaneous recovery. We herein report two cases of fulminant myocarditis following BNT162b2 mRNA Covid-19 vaccination associated with systemic hyperinflammatory syndrome and refractory shock requiring support with veno-arterial extracorporeal membrane oxygenation.

摘要

免疫介导的严重急性呼吸综合征冠状病毒 2（SARS-CoV2）感染后的心肌损伤已在成人和儿童中描述。最近有记录表明，在接种 SARS-CoV2 疫苗后会发生心肌炎，大多数与轻度严重程度和自发恢复有关。本文报告了两例 BNT162b2 mRNA COVID-19 疫苗接种后暴发性心肌炎病例，与全身高炎症综合征相关，并伴有难治性休克，需要静脉-动脉体外膜肺氧合支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/8372420/585451e0c057/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/8372420/585451e0c057/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/434b/8372420/585451e0c057/gr1_lrg.jpg

相似文献

1
Fulminant myocarditis and systemic hyperinflammation temporally associated with BNT162b2 mRNA COVID-19 vaccination in two patients.两名患者在接种 BNT162b2 mRNA COVID-19 疫苗后出现暴发性心肌炎和全身炎症反应。
Int J Cardiol. 2021 Oct 1;340:119-121. doi: 10.1016/j.ijcard.2021.08.018. Epub 2021 Aug 18.
2
Myocarditis following COVID-19 mRNA vaccination.新冠病毒mRNA疫苗接种后的心肌炎
Vaccine. 2021 Jun 29;39(29):3790-3793. doi: 10.1016/j.vaccine.2021.05.087. Epub 2021 May 28.
3
Postmarketing active surveillance of myocarditis and pericarditis following vaccination with COVID-19 mRNA vaccines in persons aged 12 to 39 years in Italy: A multi-database, self-controlled case series study.意大利 12 至 39 岁人群接种 COVID-19 mRNA 疫苗后的心肌炎和心包炎上市后主动监测：多数据库、自身对照病例系列研究。
PLoS Med. 2022 Jul 28;19(7):e1004056. doi: 10.1371/journal.pmed.1004056. eCollection 2022 Jul.
4
Myocarditis Following Immunization With mRNA COVID-19 Vaccines in Members of the US Military.mRNA COVID-19 疫苗接种后美国军人中的心肌炎。
JAMA Cardiol. 2021 Oct 1;6(10):1202-1206. doi: 10.1001/jamacardio.2021.2833.
5
Fulminant myocarditis following SARS-CoV-2 mRNA vaccination rescued with venoarterial ECMO: A report of two cases.两例 SARS-CoV-2 mRNA 疫苗接种后暴发性心肌炎应用体外膜肺氧合治疗成功的报告
Perfusion. 2024 May;39(4):655-659. doi: 10.1177/02676591231170480. Epub 2023 Apr 19.
6
Tolerability of COVID-19 Infection and Messenger RNA Vaccination Among Patients With a History of Kawasaki Disease.川崎病病史患者对 COVID-19 感染和信使 RNA 疫苗接种的耐受性。
JAMA Netw Open. 2022 Aug 1;5(8):e2226236. doi: 10.1001/jamanetworkopen.2022.26236.
7
Fulminant necrotizing eosinophilic myocarditis after COVID-19 vaccination survived with mechanical circulatory support.COVID-19 疫苗接种后暴发性坏死性嗜酸性心肌炎在机械循环支持下得以存活。
ESC Heart Fail. 2022 Aug;9(4):2732-2737. doi: 10.1002/ehf2.13962. Epub 2022 May 26.
8
Cardiac Complications After SARS-CoV-2 Infection and mRNA COVID-19 Vaccination - PCORnet, United States, January 2021-January 2022.SARS-CoV-2 感染和 mRNA COVID-19 疫苗接种后的心脏并发症 - PCORnet，美国，2021 年 1 月至 2022 年 1 月。
MMWR Morb Mortal Wkly Rep. 2022 Apr 8;71(14):517-523. doi: 10.15585/mmwr.mm7114e1.
9
Vaccination-Associated Myocarditis and Myocardial Injury.疫苗接种相关心肌炎和心肌损伤。
Circ Res. 2023 May 12;132(10):1338-1357. doi: 10.1161/CIRCRESAHA.122.321881. Epub 2023 May 11.
10
Myocarditis following mRNA Covid-19 vaccination: A pooled analysis.新型冠状病毒肺炎mRNA疫苗接种后的心肌炎：一项汇总分析。
Vaccine. 2022 Mar 15;40(12):1768-1774. doi: 10.1016/j.vaccine.2022.02.017. Epub 2022 Feb 7.

引用本文的文献

1
Cardiac and Neurological Complications Post COVID-19 Vaccination: A Systematic Review of Case Reports and Case Series.新冠疫苗接种后的心脏和神经并发症：病例报告和病例系列的系统评价
Vaccines (Basel). 2024 May 24;12(6):575. doi: 10.3390/vaccines12060575.
2
Innate and adaptive immunity in acute myocarditis.急性心肌炎中的先天免疫和适应性免疫。
Int J Cardiol. 2024 Jun 1;404:131901. doi: 10.1016/j.ijcard.2024.131901. Epub 2024 Feb 23.
3
Post-COVID-19 Vaccination Myocarditis: A Histopathologic Study on a Monocentric Series of Six Cases.

本文引用的文献

1
Myocarditis and Pericarditis After Vaccination for COVID-19.接种 COVID-19 疫苗后的心肌炎和心包炎。
JAMA. 2021 Sep 28;326(12):1210-1212. doi: 10.1001/jama.2021.13443.
2
Patients With Acute Myocarditis Following mRNA COVID-19 Vaccination.mRNA COVID-19 疫苗接种后发生急性心肌炎的患者。
JAMA Cardiol. 2021 Oct 1;6(10):1196-1201. doi: 10.1001/jamacardio.2021.2828.
3
Myocarditis Following Immunization With mRNA COVID-19 Vaccines in Members of the US Military.mRNA COVID-19 疫苗接种后美国军人中的心肌炎。
新型冠状病毒肺炎疫苗接种后心肌炎：一项单中心6例系列病例的组织病理学研究
Diagnostics (Basel). 2024 Jan 19;14(2):219. doi: 10.3390/diagnostics14020219.
4
SARS-CoV-2 Related Myocarditis: What We Know So Far.新型冠状病毒2型相关心肌炎：目前我们所了解的情况。
J Clin Med. 2023 Jul 15;12(14):4700. doi: 10.3390/jcm12144700.
5
Myocarditis Following COVID-19 Vaccination: A Systematic Review.新型冠状病毒肺炎疫苗接种后心肌炎：一项系统评价
Cureus. 2023 Apr 22;15(4):e37999. doi: 10.7759/cureus.37999. eCollection 2023 Apr.
6
COVID-19 mRNA Vaccines: The Molecular Basis of Some Adverse Events.新冠病毒mRNA疫苗：一些不良事件的分子基础
Vaccines (Basel). 2023 Mar 28;11(4):747. doi: 10.3390/vaccines11040747.
7
Short term outcome of myocarditis and pericarditis following COVID-19 vaccines: a cardiac magnetic resonance imaging study.COVID-19 疫苗接种后心肌炎和心包炎的短期转归：一项心脏磁共振成像研究。
Int J Cardiovasc Imaging. 2023 May;39(5):1031-1043. doi: 10.1007/s10554-023-02799-w. Epub 2023 Mar 13.
8
Fulminant Myocarditis and Cardiogenic Shock Following COVID-19 Infection Versus COVID-19 Vaccination: A Systematic Literature Review.新型冠状病毒感染与新冠疫苗接种后暴发性心肌炎和心源性休克：一项系统文献综述
J Clin Med. 2023 Feb 25;12(5):1849. doi: 10.3390/jcm12051849.
9
Myocarditis Following COVID-19 Vaccination.接种 COVID-19 疫苗后的心肌炎。
Heart Fail Clin. 2023 Apr;19(2):251-264. doi: 10.1016/j.hfc.2022.08.012.
10
Cardiovascular complications of COVID-19 vaccines: A review of case-report and case-series studies.新型冠状病毒疫苗的心血管并发症：病例报告和病例系列研究综述。
Heart Lung. 2023 May-Jun;59:173-180. doi: 10.1016/j.hrtlng.2023.02.003. Epub 2023 Feb 8.
JAMA Cardiol. 2021 Oct 1;6(10):1202-1206. doi: 10.1001/jamacardio.2021.2833.
4
Myocarditis After BNT162b2 and mRNA-1273 Vaccination.接种 BNT162b2 和 mRNA-1273 后心肌炎。
Circulation. 2021 Aug 10;144(6):506-508. doi: 10.1161/CIRCULATIONAHA.121.055913. Epub 2021 Jun 16.
5
Adult multisystem inflammatory syndrome in a patient who recovered from COVID-19 postvaccination.接种新冠疫苗后康复的患者出现成人多系统炎症综合征。
BMJ Case Rep. 2021 Apr 21;14(4):e242060. doi: 10.1136/bcr-2021-242060.
6
Temporal relation between second dose BNT162b2 mRNA Covid-19 vaccine and cardiac involvement in a patient with previous SARS-COV-2 infection.BNT162b2 mRNA新冠疫苗第二剂与既往感染过SARS-CoV-2的患者心脏受累之间的时间关系。
Int J Cardiol Heart Vasc. 2021 Jun;34:100774. doi: 10.1016/j.ijcha.2021.100774. Epub 2021 Mar 31.
7
Management perspectives from the 2019 Wuhan international workshop on fulminant myocarditis.2019 年武汉暴发性心肌炎国际研讨会的管理视角。
Int J Cardiol. 2021 Feb 1;324:131-138. doi: 10.1016/j.ijcard.2020.10.063. Epub 2020 Oct 26.
8
Cardiogenic Shock and Hyperinflammatory Syndrome in Young Males With COVID-19.新冠病毒肺炎（COVID-19）感染年轻男性患者的心源性休克和高炎症综合征
Circ Heart Fail. 2020 Oct;13(10):e007485. doi: 10.1161/CIRCHEARTFAILURE.120.007485. Epub 2020 Aug 26.
9
Cardiac MRI in Children with Multisystem Inflammatory Syndrome Associated with COVID-19.COVID-19 相关多系统炎症综合征患儿的心脏 MRI。
Radiology. 2020 Dec;297(3):E283-E288. doi: 10.1148/radiol.2020202288. Epub 2020 Jun 9.
10
Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19).新冠肺炎（COVID-19）患者的心脏受累。
JAMA Cardiol. 2020 Jul 1;5(7):819-824. doi: 10.1001/jamacardio.2020.1096.