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治疗超声治疗慢性鼻-鼻窦炎的系统评价。

Therapeutic ultrasound as a treatment for chronic rhinosinusitis: A systematic review.

机构信息

Department of Immunology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.

Physiotherapy Department, University of Southern Santa Catarina, Palhoça, Santa Catarina, Brazil.

出版信息

Clin Respir J. 2021 Dec;15(12):1275-1285. doi: 10.1111/crj.13441. Epub 2021 Aug 29.

Abstract

OBJECTIVE

To investigate the effects of therapeutic ultrasound in symptoms of patients with chronic rhinosinusitis.

DATA SOURCE AND STUDY SELECTION

Searches were carried out in the MEDLINE (via OVID), SCOPUS, PubMed and Virtual Health Library databases. The study selection is as follows: Pre-experimental and experimental studies in English, Spanish and Portuguese that evaluated the effects of ultrasound on the signs and symptoms of patients with chronic rhinosinusitis were included. After study selection, data extraction, risk of bias and quality assessment, we performed a qualitative description of current data.

RESULTS

Nine studies were selected, providing 309 participants (20 to 47 volunteers in each study), with an average age of 44.5 years. Three studies had assumed pretest-posttest design, four studies were single-blinded randomized controlled trial and the two studies were double-blinded randomized controlled trial. The modalities of ultrasound investigated were pulsed and continuous, and the studies evaluated the ultrasound effects immediately after one session or after a few sessions of treatment (6, 10 or 15 sessions). The use of ultrasound, in both continuous and pulsed modalities, demonstrated to reduce characteristic signs and symptoms of chronic rhinosinusitis. Despite these results, only two studies had a low risk of bias. A meta-analysis was not possible due to the huge heterogeneity of included studies.

CONCLUSIONS

Despite ultrasound in continuous and pulsed modalities showing similar positive effects in the treatment of chronic rhinosinusitis, the studies are small, short duration, poor design and with a high risk of bias. Thereby, ultrasound cannot be appointed as a potential adjunct resource to current methods of treating chronic rhinosinusitis until large randomised controlled studies are performed.

摘要

目的

研究治疗性超声波对慢性鼻-鼻窦炎患者症状的影响。

资料来源和研究选择

在 MEDLINE(通过 OVID)、SCOPUS、PubMed 和虚拟健康图书馆数据库中进行了检索。研究选择如下:纳入了评估超声对慢性鼻-鼻窦炎患者体征和症状影响的英文、西班牙文和葡萄牙文的预实验和实验研究。经过研究选择、数据提取、偏倚风险和质量评估后,我们对现有数据进行了定性描述。

结果

选择了 9 项研究,共纳入 309 名参与者(每项研究中 20 至 47 名志愿者),平均年龄为 44.5 岁。3 项研究采用了预测试-后测试设计,4 项研究为单盲随机对照试验,2 项研究为双盲随机对照试验。研究中考察的超声波模式为脉冲和连续,评估了单次治疗后或治疗 6、10 或 15 次后即刻的超声效果。连续和脉冲模式的超声均显示出可减轻慢性鼻-鼻窦炎的特征性体征和症状。尽管如此,仅有 2 项研究的偏倚风险较低。由于纳入研究的异质性很大,因此无法进行荟萃分析。

结论

尽管连续和脉冲模式的超声在治疗慢性鼻-鼻窦炎方面显示出相似的积极效果,但这些研究规模较小、持续时间短、设计较差且存在较高的偏倚风险。因此,在进行大规模随机对照研究之前,超声不能被指定为治疗慢性鼻-鼻窦炎的现有方法的潜在辅助资源。

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