Campanacci M, Giunti A, Martucci E, Trentani C
Ital J Orthop Traumatol. 1977 Apr;3(1):67-74.
A fully documented series of thirty nine cases of epiphyseal chondroblastoma is described. This is a remarkable series because of the rarity of this tumour. There is a slight predilection for the male sex. The age most affected is ten to twenty years. The tumour progresses slowly and joint involvement and pain are slight. The commonest site is the proximal epiphysis of the humerus, followed by the epiphyses of the knee. The classical appearances are of a clearly defined area of osteolysis, central or eccentric, with foci of calcification, in the epiphyseal or apophyseal regions, and often transgressing the epiphyseal cartilage. We have never observed involvement of the opposite bone in the affected joint. In four of our thirty nine cases the neoplasm invaded the point and/or soft tissues. The differential diagnosis, especially in localisations at the knee, is with giant cell tumour. The tumour is slow growing and the prognosis is always good. We have never seen malignant transformations or so-called "benign" pulmonary metastases. The few recurrences in this series (five out of thirty nine) were all cured by a second operation. Curettage and grafting is the operation of choice.
本文描述了一组完整记录的39例骨骺软骨母细胞瘤病例。由于该肿瘤罕见,这是一个值得注意的病例系列。该肿瘤略倾向于男性。最常受累的年龄为10至20岁。肿瘤进展缓慢,关节受累及疼痛轻微。最常见的部位是肱骨近端骨骺,其次是膝关节骨骺。典型表现为在骨骺或骨骺旁区域有一个界限清楚的骨质溶解区,可为中心性或偏心性,伴有钙化灶,且常跨越骨骺软骨。我们从未观察到患侧关节对侧骨骼受累。在我们的39例病例中,有4例肿瘤侵犯了骨端和/或软组织。鉴别诊断,尤其是在膝关节部位,需与骨巨细胞瘤相鉴别。该肿瘤生长缓慢,预后总是良好。我们从未见过恶性转化或所谓的“良性”肺转移。该系列中的少数复发病例(39例中有5例)均通过二次手术治愈。刮除术和植骨术是首选的手术方式。