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A clinically significant interaction between ciprofloxacin and theophylline.

作者信息

Thomson A H, Thomson G D, Hepburn M, Whiting B

机构信息

Department of Materia Medica, University of Glasgow, UK.

出版信息

Eur J Clin Pharmacol. 1987;33(4):435-6. doi: 10.1007/BF00637645.

Abstract

We report a case of theophylline toxicity following the co-administration of ciprofloxacin. Total theophylline clearance fell from 2.3 l.h-1 to 0.8 l.h-1 when ciprofloxacin was added to the treatment regimen and returned to 2.1 l.h-1 after ciprofloxacin was discontinued.

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