奎宁致盲的实验研究。
An experimental study of quinine blindness.
作者信息
Buchanan T A, Lyness R W, Collins A D, Gardiner T A, Archer D B
机构信息
Department of Ophthalmology, Royal Victoria Hospital, Belfast, Northern Ireland.
出版信息
Eye (Lond). 1987;1 ( Pt 4):522-4. doi: 10.1038/eye.1987.78.
PMID:3443206
Abstract
An experimental model of quinine induced blindness is presented. Electrophysiological, angiographical and morphological examinations were made. The occurrence of blindness and any recovery from blindness was dependent upon the dose of quinine taken. As no evidence of acute retinal ischaemia was found it is concluded that quinine is retinotoxic.
摘要
本文介绍了一种奎宁致盲的实验模型。进行了电生理、血管造影和形态学检查。失明的发生及失明后的恢复情况取决于奎宁的服用剂量。由于未发现急性视网膜缺血的证据，因此得出结论：奎宁具有视网膜毒性。
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引用本文的文献
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Research into quinine ocular toxicity.奎宁眼部毒性的研究。
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