Demeyer Heleen, Mohan Divya, Burtin Chris, Vaes Anouk W, Heasley Matthew, Bowler Russell P, Casaburi Richard, Cooper Christopher B, Corriol-Rohou Solange, Frei Anja, Hamilton Alan, Hopkinson Nicholas S, Karlsson Niklas, Man William D-C, Moy Marilyn L, Pitta Fabio, Polkey Michael I, Puhan Milo, Rennard Stephen I, Rochester Carolyn L, Rossiter Harry B, Sciurba Frank, Singh Sally, Tal-Singer Ruth, Vogiatzis Ioannis, Watz Henrik, Lummel Rob Van, Wyatt Jeremy, Merrill Debora D, Spruit Martijn A, Garcia-Aymerich Judith, Troosters Thierry
Department of Rehabilitation Sciences, KU Leuven-University of Leuven and Respiratory Division, University Hospitals Leuven, Leuven, Belgium.
Department of Rehabilitation Sciences, Ghent University, Ghent, Belgium.
Chronic Obstr Pulm Dis. 2021 Oct 28;8(4):528-550. doi: 10.15326/jcopdf.2021.0213.
Physical activity (PA) is of key importance for health among healthy persons and individuals with chronic obstructive pulmonary disease (COPD). PA has multiple dimensions that can be assessed and quantified objectively using activity monitors. Moreover, as shown in the published literature, variable methodologies have been used to date to quantify PA among individuals with COPD, precluding clear comparisons of outcomes across studies. The present paper aims to provide a summary of the available literature for the rationale behind using objectively measured PA and proposes a standardized methodology for assessment, including standard operating procedures for future research. The present paper, therefore, describes the concept of PA, reports on the importance of PA, summarizes the dimensions of PA, provides a standard operating procedure on how to monitor PA using objective assessments, and describes the psychometric properties of objectively measured PA. The present international task force recommends implementation of the standard operating procedure for PA data collection and reporting in the future. This should further clarify the relationship between PA and clinical outcomes, test the impact of treatment interventions on PA in individuals with COPD, and successfully propose a PA endpoint for regulatory qualification in the future.
身体活动（PA）对健康人群和慢性阻塞性肺疾病（COPD）患者的健康至关重要。PA具有多个维度，可以使用活动监测器进行客观评估和量化。此外，正如已发表的文献所示，迄今为止，已采用多种不同方法来量化COPD患者的PA，这使得各研究结果之间无法进行明确比较。本文旨在总结现有文献中关于使用客观测量的PA的理论依据，并提出一种标准化的评估方法，包括未来研究的标准操作程序。因此，本文描述了PA的概念，报告了PA的重要性，总结了PA的维度，提供了关于如何使用客观评估监测PA的标准操作程序，并描述了客观测量的PA的心理测量特性。本国际特别工作组建议未来实施PA数据收集和报告的标准操作程序。这应能进一步阐明PA与临床结果之间的关系，测试治疗干预对COPD患者PA的影响，并成功提出一个用于未来监管认证的PA终点指标。
