共沉淀法制备光致发光铈（III）和铈（IV）取代羟基磷灰石纳米材料的合成与表征：细胞毒性和生物相容性评价
Synthesis and Characterization of Photoluminescent Ce(III) and Ce(IV) Substituted Hydroxyapatite Nanomaterials by Co-Precipitation Method: Cytotoxicity and Biocompatibility Evaluation.
作者信息
Paduraru Andrei Viorel, Musuc Adina Magdalena, Oprea Ovidiu Cristian, Trusca Roxana, Iordache Florin, Vasile Bogdan Stefan, Andronescu Ecaterina
机构信息
Faculty of Applied Chemistry and Materials Science, Department of Science and Engineering of Oxide Materials and Nanomaterials, University "Politehnica" of Bucharest, 060042 Bucharest, Romania.
National Centre for Micro and Nanomaterials, University "Politehnica" of Bucharest, 060042 Bucharest, Romania.
出版信息
Nanomaterials (Basel). 2021 Jul 25;11(8):1911. doi: 10.3390/nano11081911.
Improved compounds of Ce(III) and Ce(IV)-doped hydroxyapatite (CaCe(PO)(OH)) with different concentrations such as x = 0.5, 1, 2.5, 5, and 10%, obtained by the simple co-precipitation method were synthesized. The cerium (3) and cerium (4)-doped hydroxyapatite were evaluated for biocompatibility and fluorescence properties. It was found that the cerium-HAp powders were non-toxic, even at higher level of concentration. The synthesized powders were further characterized by FTIR spectrometry, UV-Vis spectroscopy, XRD diffraction, SEM and TEM analysis. Therefore, the present study proves that the developed cerium (3) and cerium (4)-doped hydroxyapatite, respectively can be widely used as luminescent labeling materials, with improved biological properties.
通过简单共沉淀法合成了不同浓度（如x = 0.5%、1%、2.5%、5%和10%）的铈（III）和铈（IV）掺杂羟基磷灰石（CaCe(PO)(OH)）的改良化合物。对铈（3）和铈（4）掺杂的羟基磷灰石进行了生物相容性和荧光特性评估。结果发现，即使在较高浓度水平下，铈掺杂羟基磷灰石粉末也是无毒的。通过傅里叶变换红外光谱法、紫外可见光谱法、X射线衍射、扫描电子显微镜和透射电子显微镜分析对合成的粉末进行了进一步表征。因此，本研究证明，所开发的铈（3）和铈（4）掺杂羟基磷灰石分别可作为具有改善生物学特性的发光标记材料广泛应用。
Zotero 插件