温度对人皮肤中8-甲氧基补骨脂素皮肤光毒性反应的影响。
Effect of temperature on the cutaneous phototoxic reaction to 8-methoxypsoralen in human skin.
作者信息
Youn J I, Maytum D, Gange R W
机构信息
Wellman Laboratory, Massachusetts General Hospital, Boston.
出版信息
Photodermatol. 1987 Dec;4(6):277-80.
PMID:3444754
Abstract
Phototoxic erythema in human skin resulting from topical 8-methoxypsoralen (8-MOP) + UVA exposure was examined at different skin temperatures. Increased skin temperature resulting from radiant or conductive heating during UVA exposure decreased the ensuing phototoxic response. Preheating the skin for 30 min prior to UVA exposure caused a greater decrease in phototoxicity.
摘要
在不同皮肤温度下，研究了局部应用8-甲氧基补骨脂素（8-MOP）加紫外线A（UVA）照射引起的人体皮肤光毒性红斑。UVA照射期间因辐射或传导加热导致的皮肤温度升高降低了随后的光毒性反应。在UVA照射前将皮肤预热30分钟导致光毒性有更大程度的降低。
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