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荧光增强治疗学:可视化、检测和去除龋齿的新方法。

Fluorescence-Enhanced Theragnosis: A Novel Approach to Visualize, Detect, and Remove Caries.

机构信息

Clinical Professor, Department of Preventive and Restorative Sciences, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania.

Professor of Oral Biology and Endodontology, Vice-Provost (Research), Federal University of Rio Grande do Sul, Porto Alegre/RS, Brazil.

出版信息

Compend Contin Educ Dent. 2021 Sep;42(8):460-465.

PMID:34449243
Abstract

Fluorescence tools have shown to be highly valuable for precise diagnosis of caries and other lesions in dentistry. In the form of ultraviolet (UV) headlights and special loupes with high levels of magnification and observational capacity, these instruments can even be used during treatment for a more preventive and minimally invasive treatment strategy. Fluorescence, a type of luminescence, absorbs light of shorter wavelength and re-emits it as longer-wavelength light. This changes the color, for example from blue to red. The fluorescence spectra of carious lesions are typical for fluorescent porphyrins, mainly protoporphyrin IX. A possible source of these porphyrins within carious tissues is bacterial biosynthesis. Streptococcus mutans induces enamel and dentin lesions and modifies the fluorescence in the red and green spectral regions, with a stronger signal in the red region, due to porphyrin gradient signals. This article describes the concept of fluorescence-enhanced theragnosis for removal of caries and preservation of sound dental tissues.

摘要

荧光工具已被证明对口腔龋齿和其他病变的精确诊断具有很高的价值。这些工具以紫外线(UV)车头灯和具有高倍率和观察能力的特殊双光眼镜的形式存在,甚至可以在治疗过程中使用,以实现更具预防性和微创性的治疗策略。荧光是一种发光形式,它吸收较短波长的光,然后重新发射出较长波长的光。这会改变颜色,例如从蓝色变为红色。龋齿病变的荧光光谱是荧光卟啉的典型特征,主要是原卟啉 IX。龋齿组织中这些卟啉的一个可能来源是细菌生物合成。变形链球菌会引起牙釉质和牙本质病变,并改变红色和绿色光谱区域的荧光,红色区域的信号更强,这是由于卟啉梯度信号。本文介绍了荧光增强治疗龋齿和保护健康牙齿组织的概念。

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Compend Contin Educ Dent. 2021 Sep;42(8):460-465.
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