Center for Behavioral Science Research, Department of Health Policy & Health Services Research, Henry M. Goldman School of Dental Medicine, Boston University, Boston, MA, USA.
Center of Alcohol and Substance Use Studies, Department of Applied Psychology, Rutgers University, Piscataway, NJ, USA.
Ann Behav Med. 2022 Aug 30;56(9):890-899. doi: 10.1093/abm/kaab077.
In the general population, quitting smoking is associated with improved health-related quality of life (QoL), but this association has not been examined in smokers with chronic mobility impairments (MIs).
We examined associations between smoking status and health-related QoL over 6 months, and whether relationships are moderated by depression and MI severity.
This is a secondary analysis of a smoking cessation induction trial among smokers with MIs (n = 241, 56% female, 36% Black) assessed at baseline, and 4 and 6 months after. Participants were grouped into "Smokers" (smoking at 4 and 6 months), "Abstainers" (quit at 4 and 6 months), "Relapsers" (relapsed at 6 months), and "Late-quitters" (quit at 6 months). Physical and mental health-related QoL was assessed with the Short-Form Health Survey. Depression was defined as scores ≥10 on the Patient Health Questionnaire, and MI severity by the use of skilled care for personal needs. Data were analyzed with linear mixed models.
Aggregating across time, among nondepressed participants, compared with "Smokers," the "Abstainer," and "Late-quitter" groups improved their physical health scores. "Late-quitters" also improved compared with "Relapsers." Among the total sample, compared with "Smokers," "Abstainers" showed improvements in mental health scores overtime, whereas "Relapsers" improved their score at 4 months, and "Late-quitters" improved at 6 months.
Quitting smoking is associated with improvements in physical health-related QoL regardless of the severity of MI but only among those without depression at baseline. For mental health-related QoL, associations with quitting smoking were independent of baseline depression and severity of MI.
在普通人群中,戒烟与健康相关生活质量(QoL)的改善有关,但尚未在患有慢性运动障碍(MI)的吸烟者中进行过此类研究。
我们检查了吸烟状况与 6 个月内健康相关 QoL 的关联,以及抑郁和 MI 严重程度是否调节了这些关系。
这是一项针对患有 MI 的吸烟者(n=241,56%为女性,36%为黑人)的戒烟诱导试验的二次分析,这些吸烟者在基线、4 个月和 6 个月时接受了评估。参与者分为“吸烟者”(在 4 个月和 6 个月时吸烟)、“戒烟者”(在 4 个月和 6 个月时戒烟)、“复吸者”(在 6 个月时复吸)和“延迟戒烟者”(在 6 个月时戒烟)。采用简明健康调查量表评估身体和心理健康相关 QoL。抑郁定义为患者健康问卷得分≥10,MI 严重程度通过使用熟练护理满足个人需求来衡量。采用线性混合模型进行数据分析。
在非抑郁参与者中,与“吸烟者”相比,“戒烟者”和“延迟戒烟者”在所有时间点的身体健康评分都有所提高。“延迟戒烟者”与“复吸者”相比也有所提高。在总样本中,与“吸烟者”相比,“戒烟者”的心理健康评分随时间逐渐提高,而“复吸者”在 4 个月时提高了评分,“延迟戒烟者”在 6 个月时提高了评分。
无论 MI 的严重程度如何,戒烟与身体健康相关 QoL 的改善有关,但仅在基线时无抑郁的患者中如此。对于心理健康相关 QoL,与戒烟相关的关联与基线抑郁和 MI 的严重程度无关。