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使用牙种植体对一名低磷酸酯酶症患者进行口腔修复:一项七年随访的病例报告

Prosthodontic Rehabilitation of a Patient with Hypophosphatasia Using Dental Implants: A Case Report with Seven Years Follow-Up.

作者信息

Yang Yundong, Liu Zhonghao, Wei Lingfei, Taylor Thomas D, Xiao Huijuan

机构信息

Department of Reconstructive Dentistry, Yantai Stomatological Hospital Development Zone Branch, Shandong Province, PR China.

Binzhou Medical College; Department of Implant Dentistry, Yantai Stomatological Hospital, Shandong Province, PR China.

出版信息

J Prosthodont. 2021 Dec;30(9):742-746. doi: 10.1111/jopr.13419. Epub 2021 Sep 8.

DOI:10.1111/jopr.13419
PMID:34453769
Abstract

Hypophosphatasia is a rare metabolic inherited dento-osseous disorder. Although there is some available literature on various dental characteristics of hypophosphatasia patients, few reports focus on the effects of hypophosphatasia on the permanent dentition and prosthodontic rehabilitation, particularly in relation to the use of dental implants. This paper reports a case with hypophosphatasia and prosthodontic rehabilitation using dental implants with 7-year follow-up.

摘要

低磷酸酯酶症是一种罕见的遗传性代谢性牙骨质骨发育异常疾病。尽管有一些关于低磷酸酯酶症患者各种牙齿特征的文献,但很少有报告关注低磷酸酯酶症对恒牙列及口腔修复治疗的影响,尤其是与牙种植体使用相关的影响。本文报告了一例低磷酸酯酶症患者使用牙种植体进行口腔修复治疗并随访7年的病例。

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引用本文的文献

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Decade-long delayed diagnosis of hypophosphatasia until next generation tooth loss: case reports on dental rehabilitation, diagnostic challenges and clinical implications.低磷酸酯酶症长达十年的延迟诊断直至下一代牙齿脱落:关于牙齿修复、诊断挑战及临床意义的病例报告
Front Oral Health. 2025 Jul 18;6:1585188. doi: 10.3389/froh.2025.1585188. eCollection 2025.
2
Dental manifestations of hypophosphatasia: translational and clinical advances.低磷酸酯酶症的口腔表现:转化医学与临床进展
JBMR Plus. 2025 Jan 6;9(2):ziae180. doi: 10.1093/jbmrpl/ziae180. eCollection 2025 Feb.
3
Inherited phosphate and pyrophosphate disorders: New insights and novel therapies changing the oral health landscape.
遗传性磷酸盐和焦磷酸盐代谢紊乱:新的认识和新的治疗方法正在改变口腔健康状况。
J Am Dent Assoc. 2024 Nov;155(11):912-925. doi: 10.1016/j.adaj.2024.05.016. Epub 2024 Aug 10.
4
Dental manifestation and management of hypophosphatasia.低磷酸酯酶症的口腔表现及处理
Jpn Dent Sci Rev. 2022 Nov;58:208-216. doi: 10.1016/j.jdsr.2022.06.002. Epub 2022 Jul 2.